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      Management of Cataract in Patients with Irregular Astigmatism with Regular Central Component by Phacoemulsification Combined with Toric Intraocular Lens Implantation

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      Journal of Ophthalmology
      Hindawi

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          Abstract

          Purpose

          To evaluate visual acuity (VA) and refractive status in patients with cataract and irregular astigmatism with a regular central component after phacoemulsification with implantation of a toric intraocular lens (IOL).

          Methods

          Patients with cataract associated with irregular astigmatism with a regular central component were enrolled. All patients underwent phacoemulsification and toric IOL implantation. Postoperative visual acuity, residual astigmatism, toric IOL rotation, higher-order aberration, and objective and subjective visual quality were measured 3 months after surgery.

          Results

          Twenty-three eyes were included in the study. The logMAR corrected and uncorrected distance visual acuity values were decreased at 3 months postoperatively ( p  <  0.005). The preoperative average corneal astigmatism and postoperative residual astigmatism were 1.15–6.97 D (1.99 ± 1.26 D) and 0–2.75 D (0.65 ± 0.57 D), respectively. The average IOL rotation was 3.17 ± 2.01°. Some objective indicators of visual quality, including the modulation transfer function ( p  <  0.05), Strehl ratio ( p  <  0.005), 100% VA ( p  <  0.005), 20% VA ( p  <  0.005), and 9% VA ( p  <  0.005), were significantly higher than the corresponding preoperative values. The objective scatter index ( p  <  0.005) was significantly lower than that before surgery. The postoperative VF-14 scale score was 83.99 ± 14.58.

          Conclusion

          Toric IOL implantation has a good corrective effect on certain specific types of corneal irregular astigmatism with cataract. This effect can be attributed to its ability to correct the regular component of irregular astigmatism. The indications for toric IOL implantation could be expanded to some extent, thereby bringing benefit to more patients.

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          Most cited references42

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          Correcting astigmatism with toric intraocular lenses: effect of posterior corneal astigmatism.

          To evaluate the impact of posterior corneal astigmatism on outcomes with toric intraocular lenses (IOLs). Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, USA. Case series. Corneal astigmatism was measured using 5 devices before and 3 weeks after cataract surgery. Toric IOL alignment was recorded at surgery and at the slitlamp 3 weeks postoperatively. The actual corneal astigmatism was calculated based on refractive astigmatism 3 weeks postoperatively and the effective toric power calculated with the Holladay 2 formula. The prediction error was calculated as the difference between the astigmatism measured by each device and the actual corneal astigmatism. Vector analysis was used in all calculations. With the IOLMaster, Lenstar, Atlas, manual keratometer, and Galilei (combined Placido-dual Scheimpflug analyzer), the mean prediction errors (D) were, respectively, 0.59 @ 89.7, 0.48 @ 91.2, 0.51 @ 78.7, 0.62 @ 97.2, and 0.57 @ 93.9 for with-the-rule (WTR) astigmatism (60 to 120 degrees), and 0.17 @ 86.2, 0.23 @ 77.7, 0.23 @ 91.4, 0.41 @ 58.4, and 0.12 @ 7.3 for against-the-rule (ATR) astigmatism (0 to 30 degrees and 150 to 180 degrees). In the WTR eyes, there were significant WTR prediction errors (0.5 to 0.6 diopters [D]) by all devices. In ATR eyes, WTR prediction errors were 0.2 to 0.3 D by all devices except the Placido-dual Scheimpflug analyzer (all P<.05 with Bonferroni correction). Corneal astigmatism was overestimated in WTR by all devices and underestimated in ATR by all except the Placido-dual Scheimpflug analyzer. A new toric IOL nomogram is proposed. Copyright © 2013 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.
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            Toric intraocular lenses: historical overview, patient selection, IOL calculation, surgical techniques, clinical outcomes, and complications.

            We present an overview of currently available toric intraocular lenses (IOLs) and multifocal toric IOLs. Relevant patient selection criteria, IOL calculation issues, and surgical techniques for IOL implantation are discussed. Clinical outcomes including uncorrected visual acuity, residual refractive astigmatism, and spectacle independency, which have been reported for both toric IOLs and multifocal toric IOLs, are reviewed. The incidence of misalignment, the most important complication of toric IOLs, is determined. Finally, future developments in the field of toric IOLs are discussed.
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              The AcrySof Toric intraocular lens in subjects with cataracts and corneal astigmatism: a randomized, subject-masked, parallel-group, 1-year study.

              To compare the AcrySof Toric intraocular lens (IOL) and an AcrySof spherical control IOL and to investigate rotational stability of the AcrySof Toric IOL (Alcon Laboratories, Inc., Fort Worth, TX) in subjects with cataracts and preexisting corneal astigmatism. Randomized, subject-masked, parallel-group, multicenter, 1-year study. We included 517 subjects (Toric IOL, n = 256; control IOL, n = 261). Unilateral implantation of an AcrySof Toric or AcrySof spherical control IOL (spherical powers, 12.00-25.00 diopters [D]; cylinder powers 1.50, 2.25, or 3.00 D for corneal astigmatism correction of 0.75 to < 1.50, ≥ 1.50 to <2.00, and ≥ 2.00 D with no upper limit, respectively). No limbal relaxing incisions were permitted. Visual acuity outcomes, IOL position, patient-reported spectacle use, and safety. One year postoperatively, best spectacle-corrected distance visual acuity of ≥ 20/20 was 77.7% (Toric IOL) versus 69.2% (control IOL). Uncorrected distance visual acuity of 20/20 or better was 40.7% (Toric IOL) versus 19.4% (control IOL; P<0.05). Mean absolute residual refractive cylinder was 0.59 D (Toric IOL) versus 1.22 D (control IOL; P<0.0001). Mean rotation was < 4° (range, 0°-20°) for the Toric IOL. Six-month spectacle freedom was 61.0% (Toric IOL) and 36.4% (control IOL; P < 0.0001). Complications in both groups were few and were as would be expected with cataract surgery. Favorable efficacy, rotational stability, distance vision spectacle freedom, and safety results support the use of the AcrySof Toric IOL for patients with cataracts and corneal astigmatism. Proprietary or commercial disclosure may be found after the references. Copyright © 2010 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.
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                Author and article information

                Contributors
                Journal
                J Ophthalmol
                J Ophthalmol
                JOPH
                Journal of Ophthalmology
                Hindawi
                2090-004X
                2090-0058
                2020
                30 April 2020
                : 2020
                : 3520856
                Affiliations
                Department of Ophthalmology, The General Hospital of the People's Liberation Army, Beijing 100000, China
                Author notes

                Academic Editor: Miguel Rechichi

                Author information
                https://orcid.org/0000-0001-9141-7765
                https://orcid.org/0000-0001-8660-3037
                https://orcid.org/0000-0002-2468-1758
                https://orcid.org/0000-0003-0807-2490
                https://orcid.org/0000-0001-8767-6721
                https://orcid.org/0000-0002-8197-9542
                Article
                10.1155/2020/3520856
                7210554
                32411427
                eb79b2eb-e8fa-4e79-967c-2b8954304d90
                Copyright © 2020 Yi Gao et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 17 December 2019
                : 23 March 2020
                Funding
                Funded by: National Natural Science Foundation of China
                Award ID: 81870640
                Award ID: 81670838
                Funded by: Beijing Municipal Natural Science Foundation
                Award ID: 7182152
                Categories
                Clinical Study

                Ophthalmology & Optometry
                Ophthalmology & Optometry

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