Diagnostic Value of CT Angiography Combined with High-Resolution Magnetic Resonance Angiography in Vascular Lesions in Acute Stroke

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Abstract

Cerebrovascular disease is increasing rapidly because of its high morbidity and high mortality, which is a serious threat to human health. For the early diagnosis and treatment of diseases, the CT vascular noise combined with high-resolution magnetic resonance angiography in acute cerebral apoplexy vascular disease is adopted. 150 patients with ischemic stroke were selected, which were admitted to the Department of Radiology, Huizhou Central People’s Hospital, from January 2020 to December 2020. All patients accepted digital subtraction angiography (DSA), magnetic resonance angiography (MRA), and CT angiography (CTA) examination. Results. There were 76 cases of aneurysm in DSA examination, accounting for 46%; 69 cases with pulsating stenosis, accounting for 50.67%; and 5 cases of moyamoya disease, accounting for 3.33%. The number and proportion of cases of the above diseases in MRA examination were (75, 69, 71; 53.33%, 45.67%, 4%), and those in CTA examination were (71, 76, 3, 47.33%, 50.67%, 2%). Relative to the DSA gold standard, the sensitivity, specificity, and false positive rate of MRA were 81.51%, 95.19%, and 2.1, respectively, and those of CTA were 95.78%, 79.17%, and 11.0, respectively. The number of cases and accuracy of detection of cerebral aneurysms by MRA were (75, 96.57%), and those by CTA were (71, 91.2%), which was not statistically considerable, $P > 0.05$ . For the number of cases and the detection accuracy of cerebrovascular malformations, MRA was (38, 92.68%) and CTA was (37, 90.24%), which was not statistically considerable, $P > 0.05$ . Conclusion. The detection sensitivity and accuracy of MRA were better than those of CTA, while specific CTA was superior to MRA. The differences between the two detections were substantial ( $P < 0.05$ ), while the sensitivity and false positive rate were not remarkably different ( $P > 0.05$ ). Therefore, the combination of the two detections was of great significance to the diagnosis and treatment of stroke and other vascular diseases.

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Record: found
Abstract: not found
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Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment

B Love, D L Gordon, J. Biller … (1993)

0 comments Cited 900 times – based on 0 reviews      Review now

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Record: found
Abstract: found
Article: not found

The detection and management of unruptured intracranial aneurysms.

Andrew Wardlaw, Peter S. White (2000)

The incidence of subarachnoid haemorrhage (SAH) is 6-8 per 100 000 person years, peaking in the sixth decade. SAH, mostly due to rupture of an intracranial aneurysm, accounts for a quarter of cerebrovascular deaths. Aneurysms increase in frequency with age beyond the third decade, are 1.6 times more common in women and are associated with a number of genetic conditions. Prospective autopsy and angiographic studies indicate that between 3.6 and 6% of the population harbour an intracranial aneurysm. Studies have found an increased rate of SAH in first degree relatives of SAH patients (relative risk 3.7-6.6). In affected families, the most frequent relationship between sufferers is sibling to sibling. The rupture rate of asymptomatic aneurysms was thought to be 1-2% per annum, but the recent International Study of Unruptured Intracranial Aneurysms found that the rupture rate of small aneurysms was only 0.05% per annum in patients with no prior SAH, and 0.5% per annum for large (>10 mm diameter) aneurysms and for all aneurysms in patients with previous SAH. Non-invasive tests such as magnetic resonance angiography (MRA), computed tomographic angiography (CTA) and transcranial Doppler (TCD) have been advocated as alternatives to intra-arterial digital subtraction angiography to screen for aneurysms. Although all are promising techniques, the quality of data testing their accuracy is limited. Overall reported sensitivity for CTA and MRA (TCD is poorer) was 76-98% and specificity was 85-100%, but many subjects had an aneurysm or recent SAH, which could overestimate accuracy. CTA and MRA are much poorer methods for the detection of aneurysms <5 mm diameter, which account for up to one-third of unruptured aneurysms. Elective surgical clipping of asymptomatic aneurysms has a morbidity of 10.9% and mortality of 3. 8%. Treatment of aneurysms by Guglielmi coils, for which there is less long-term follow-up available, has a 4% morbidity and 1% mortality, but only achieves complete aneurysm occlusion in 52-78% of cases. There has been interest in screening for aneurysms, but the indication for, and cost effectiveness of screening are unclear because aneurysm prevalence varies, rupture rate is low, non-invasive imaging tests are not yet accurate enough to exclude small aneurysms and the morbidity and mortality for elective surgical treatment of unruptured aneurysms is high. There may be a limited role for investigation of high risk subgroups. Ideally, screening in such subgroups should be tested in a randomized trial. The avoidance of risk factors for aneurysms such as smoking, hypertension and hypercholesterolaemia should be part of the management of at-risk subjects.

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Analysis of the clinicopathologic features of papillary thyroid microcarcinoma based on 7-mm tumor size.

S Lee, Haejun Ahn, Myeong Lee … (2011)

We examined the clinicopathologic features of papillary thyroid microcarcinomas (PTMCs) measuring≤7 mm and compared them with those of PTMCs>7 mm. Between January 2007 and June 2009, a total of 275 patients with PTMCs underwent surgery. They were divided into two groups. Group I included patients with tumors≤7 mm, and group II included those with tumors>7 mm but ≤10 mm. We compared the two groups' clinicopathologic features. Total thyroidectomy was more often performed in group II (p=0.003). Central lymph node metastases were identified in 30.6% of the patients in group I and in 47.8% of the patients in group II (p=0.005). A statistically significant difference between the two groups was also found for capsule invasion (p 7 mm. Because the aggressiveness of PTMC was found mainly in the patients with tumors >7 mm, we think that a cutoff value of 7 mm may be considered the threshold of aggressiveness of PTMCs.