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      Retinal microvascular function predicts chronic kidney disease in patients with cardiovascular risk factors.

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          Abstract

          Endothelial dysfunction is a precursor to atherosclerosis and is implicated in the coexistence between cardiovascular disease (CVD) and chronic kidney disease (CKD). We examined whether retinal microvascular dysfunction is present in subjects with renal impairment and predictive of long-term CKD progression in patients with CVD.

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          Author and article information

          Journal
          Atherosclerosis
          Atherosclerosis
          Elsevier BV
          1879-1484
          0021-9150
          Jan 2022
          : 341
          Affiliations
          [1 ] Department of Cardiology, Austin Health, Melbourne, Australia; Department of Medicine, Austin Health, The University of Melbourne, Melbourne, Australia.
          [2 ] Department of Cardiology, Austin Health, Melbourne, Australia.
          [3 ] Department of Medicine, Austin Health, The University of Melbourne, Melbourne, Australia.
          [4 ] The Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Australia; Ophthalmology, Department of Surgery, The University of Melbourne, Melbourne, Australia.
          [5 ] Singapore Eye Research Institute, Singapore National Eye Centre, Duke-NUS Medical School, National University of Singapore, Singapore.
          [6 ] Department of Nephrology, St. Vincent's Hospital, Melbourne, Australia.
          [7 ] Department of Cardiology, Austin Health, Melbourne, Australia; Department of Medicine, Austin Health, The University of Melbourne, Melbourne, Australia. Electronic address: omar.farouque@austin.org.au.
          Article
          S0021-9150(21)01392-7
          10.1016/j.atherosclerosis.2021.10.008
          34756728
          eb0ee22b-2693-47fe-a961-fd02847ca4b7
          History

          Dynamic vessel analysis,Chronic kidney disease,Endothelial function,Microvascular dysfunction,Renal impairment,Retinal circulation

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