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      Preliminary study on the computer-based optokinetic nystagmus analyzer to detect the visual acuity of preschool children

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          Abstract

          The purpose of this study is to examine the viability, precision, and consistency of a computer-based optokinetic nystagmus analyzer (nystagmus meter) for diagnosing eyesight in preschoolers. A total of 59 subjects who could pass the log of minimum angle of resolution (LogMAR) visual acuity chart were divided into three groups by age, 4-, 5-, and 6-year-old groups, and their visual acuity was tested with nystagmus meter. The percentage of children in each age group that could be detected by nystagmus was recorded along with the differences between these groups. The correlation between the test results from the two methods was found for each age group using the correlation coefficient method. Repeated measurements were used to assess the two visual acuity values of the measured nystagmus, and the repeatability of the two measurement techniques for different age groups was compared. The overall measurability of the visual acuity detected by nystagmus was 93.22%, and the measurability of the 4-, 5-, and 6-year-old groups was 90%, 95%, and 94.74%, respectively. There was no statistically significant difference in the measurability of subjects among all age groups ( P = 1.0). The outcomes of the LogMAR visual acuity chart had a negative correlation with the visual acuity measured by the nystagmus meter. The overall correlation coefficient R value was -0.80, and the correlation coefficient R value of the 4-, 5-, and 6-year-old groups was -0.79, -0.76, and -0.87, respectively. The nystagmus meter has good feasibility, accuracy, and stability in visual acuity testing and can be used for visual acuity testing in children.

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          Video-oculography eye tracking towards clinical applications: A review

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            Cerebellar activation during optokinetic stimulation and saccades.

            To investigate the activation pattern of cerebellar structures during small-field optokinetic stimulation (OKN) by functional MRI (fMRI) and compare it with that obtained during voluntary saccades and fixation suppression of OKN. Functional images were acquired from oblique transverse slices of eight healthy, right-handed volunteers using a radio frequency-spoiled, single-slice, fast low-angle shot (FLASH) pulse sequence with high-spatial resolution. Horizontal OKN and saccades were associated with bilateral activity in the cerebellar hemispheres (superior semilunar lobule, simple lobule, quadrangular lobule, inferior semilunar lobule), the middle cerebellar peduncle, the dentate nucleus, and medially in the culmen and uvula of cerebellar nuclei. The pattern and extent of activation were independent of the stimulus direction for OKN and saccades. During fixation suppression, the extent of activation was significantly diminished (hemispheres) or even absent (uvula, culmen). The differential effects of fixation suppression on this complex pattern of cerebellar activation in part allow us to separate visual and attentional from ocular motor processing. Our data agree with behavioral and physiologic animal data about ocular motor processes and motor learning in the vestibulospinal and optokinetic reflex. This suggests that hemispheric cerebellar activity may be mainly associated with changes in attention, whereas vermal activity seems to be associated with ocular motor control, and activity of the dentate nuclei and the cerebellar peduncles seems to be associated with both.
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              PET study of voluntary saccadic eye movements in humans: basal ganglia-thalamocortical system and cingulate cortex involvement.

              1. The purpose of this work was to explore the cortical and subcortical mechanisms underlying the execution of voluntary saccadic eye movements in humans. 2. Normalized regional cerebral blood flow (NrCBF) was measured using positron emission tomography (PET) and H2(15O) bolus intravenous injections in four right-handed healthy volunteers at rest and while performing self-paced voluntary horizontal saccadic eye movements in total darkness. 3. Magnetic resonance imaging of each subject's brain was matched to PET images, allowing the detection of activation in individually defined anatomic regions of interest. Cortical regions were drawn according to gyri limits; subcortical structures were also defined. 4. Self-paced saccadic eye movements elicited bilateral NrCBF increases in the lenticular nuclei, including putamen and globus pallidus, and in the thalamus. At the cortical level, we found bilateral NrCBF increases in the precentral gyrus, the superior part of the median frontal gyrus that corresponds to the supplementary motor area. There was also a significant NrCBF increase in the cerebellar vermis. 5. Right fusiform and lingual gyri, right insula, and left cingulate gyrus were also activated during the execution of saccades. 6. These results indicate that the classical basal ganglia-thalamocortical motor loop previously described for skeletal movements may also be involved in simple saccadic eye movements in humans.
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                Author and article information

                Journal
                Indian J Ophthalmol
                Indian J Ophthalmol
                IJO
                Indian J Ophthalmol
                Indian Journal of Ophthalmology
                Wolters Kluwer - Medknow (India )
                0301-4738
                1998-3689
                February 2024
                25 January 2024
                : 72
                : Suppl 2
                : S162-S166
                Affiliations
                [1]Department of Ophthalmology, Weihai Central Hospital, Weihai, Shandong, China
                [1 ]Precision Medicine Center of Oncology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shangdong, China
                [2 ]Department of Research and Development, Pengfengcheng Medical Technology, Qingdao, Shangdong, China
                [3 ]Department of Management and Marketing, University of Petroleum Huadong, Qingdao, Shangdong, China
                Author notes
                Correspondence to: Dr. Song Yu, Department of Ophthalmology, Weihai Central Hospital, Weihai, Shandong, China. E-mail: wd_songyu@ 123456163.com
                Article
                IJO-72-162
                10.4103/IJO.IJO_2683_23
                11624647
                38271412
                eac9b419-52d9-44ff-9ff0-3aa74c1cb581
                Copyright: © 2024 Indian Journal of Ophthalmology

                This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

                History
                : 07 October 2023
                : 08 December 2023
                Categories
                Innovations in Ophthalmology

                Ophthalmology & Optometry
                accuracy,children,computer-based optokinetic nystagmus,optotypes,stability,visual acuity

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