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      A comparative study of the neuropsychiatric and neurocognitive phenotype in two microdeletion syndromes: velocardiofacial (22q11.2 deletion) and Williams (7q11.23 deletion) syndromes.

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          Abstract

          22q11.2 deletion syndrome (22q11.2DS) and Williams syndrome (WS) are common neurogenetic microdeletion syndromes. The aim of the present study was to compare the neuropsychiatric and neurocognitive phenotypes of 22q11.2DS and WS.

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          Author and article information

          Journal
          Eur. Psychiatry
          European psychiatry : the journal of the Association of European Psychiatrists
          Elsevier BV
          1778-3585
          0924-9338
          May 2014
          : 29
          : 4
          Affiliations
          [1 ] The Behavioral Neurogenetics Center, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer 52621, Israel; The Institute for Clinical Neurophysiology and Audiology, Rabin Medical Center, Petah Tikva 49202, Israel; The Interdisciplinary Ph.D. Program in Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel.
          [2 ] Department of Psychiatry, University of British Columbia & Division of Child & Adolescent Psychiatry, BC Children's Hospital, Vancouver, Canada.
          [3 ] The Behavioral Neurogenetics Center, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer 52621, Israel.
          [4 ] Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel; The Biochemical Genetics Laboratory, Felsenstein Medical Research Center, Petah Tikva 49202, Israel.
          [5 ] The Biochemical Genetics Laboratory, Felsenstein Medical Research Center, Petah Tikva 49202, Israel.
          [6 ] Department of Psychiatry, McGill University, Montreal, Canada; ABS Lab and Douglas Institute Research Center, Verdun, Canada.
          [7 ] Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel; The Nes-Ziyyona-Beer Yaakov Mental Health Center, Nes-Ziyyona 70400, Israel.
          [8 ] Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel; The Biochemical Genetics Laboratory, Felsenstein Medical Research Center, Petah Tikva 49202, Israel; Research Unit at Geha Mental Health Center, Petah Tikva 49202, Israel.
          [9 ] The Behavioral Neurogenetics Center, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer 52621, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. Electronic address: gothelf@post.tau.ac.il.
          Article
          S0924-9338(13)00097-7
          10.1016/j.eurpsy.2013.07.001
          24054518
          e8eebbea-227e-4488-9c76-03658812b171
          History

          Visuospatial functions,Williams syndrome,Psychiatric manifestation,Executive functions,22q11.2 deletion syndrome

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