100
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      The functional role of the inferior parietal lobe in the dorsal and ventral stream dichotomy

      research-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Current models of the visual pathways have difficulty incorporating the human inferior parietal lobe (IPL) into dorsal or ventral streams. Some recent proposals have attempted to integrate aspects of IPL function that were not hitherto dealt with well, such as differences between the left and right hemisphere and the role of the right IPL in responding to salient environmental events. However, we argue that these models also fail to capture adequately some important findings regarding the functions of the IPL. Here we critically appraise existing proposals regarding the functional architecture of the visual system, with special emphasis on the role of this region, particularly in the right hemisphere. We review evidence that shows the right IPL plays an important role in two different, but broadly complementary, aspects of attention: maintaining attentive control on current task goals as well as responding to salient new information or alerting stimuli in the environment. In our view, findings from functional imaging, electrophysiological and lesion studies are all consistent with the view that this region is part of a system that allows flexible reconfiguration of behaviour between these two alternative modes of operation. Damage to the right IPL leads to deficits in both maintaining attention and also responding to salient events, impairments that contribute to hemineglect, the classical syndrome that follows lesions of this region.

          Related collections

          Most cited references142

          • Record: found
          • Abstract: found
          • Article: not found

          The activation of attentional networks.

          Alerting, orienting, and executive control are widely thought to be relatively independent aspects of attention that are linked to separable brain regions. However, neuroimaging studies have yet to examine evidence for the anatomical separability of these three aspects of attention in the same subjects performing the same task. The attention network test (ANT) examines the effects of cues and targets within a single reaction time task to provide a means of exploring the efficiency of the alerting, orienting, and executive control networks involved in attention. It also provides an opportunity to examine the brain activity of these three networks as they operate in a single integrated task. We used event-related functional magnetic resonance imaging (fMRI) to explore the brain areas involved in the three attention systems targeted by the ANT. The alerting contrast showed strong thalamic involvement and activation of anterior and posterior cortical sites. As expected, the orienting contrast activated parietal sites and frontal eye fields. The executive control network contrast showed activation of the anterior cingulate along with several other brain areas. With some exceptions, activation patterns of these three networks within this single task are consistent with previous fMRI studies that have been studied in separate tasks. Overall, the fMRI results suggest that the functional contrasts within this single task differentially activate three separable anatomical networks related to the components of attention.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Decision making, the P3, and the locus coeruleus-norepinephrine system.

            Psychologists and neuroscientists have had a long-standing interest in the P3, a prominent component of the event-related brain potential. This review aims to integrate knowledge regarding the neural basis of the P3 and to elucidate its functional role in information processing. The authors review evidence suggesting that the P3 reflects phasic activity of the neuromodulatory locus coeruleus-norepinephrine (LC-NE) system. They discuss the P3 literature in the light of empirical findings and a recent theory regarding the information-processing function of the LC-NE phasic response. The theoretical framework emerging from this research synthesis suggests that the P3 reflects the response of the LC-NE system to the outcome of internal decision-making processes and the consequent effects of noradrenergic potentiation of information processing. Copyright 2005 APA, all rights reserved.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Two varieties of long-latency positive waves evoked by unpredictable auditory stimuli in man.

              Two distinct late-positive components of the scalp-recorded auditory evoked potential were identified which differed in their latency, scalp topography and psychological correlates. The earlier component, called "P3a" (latency about 240 msec), was elicited by infrequent, unpredictable shifts of either intensity or frequency in a train of tone pips whether the subject was ignoring (reading a book) or attending to the tones (counting). The later component, called "P3a" (mean latency about 350 msec), occurred only when the subject was actively attending to the tones; it was evoked by the infrequent, unpredictable stimulus shifts, regardless of whether the subject was counting that stimulus or the more frequently occurring stimulus. Both of these distinct psychophysiological entities have previously been refered to as the "P3" or "P300" in the literature.
                Bookmark

                Author and article information

                Journal
                Neuropsychologia
                Neuropsychologia
                Pergamon Press
                0028-3932
                1873-3514
                May 2009
                May 2009
                : 47
                : 6
                : 1434-1448
                Affiliations
                UCL Institute of Cognitive Neuroscience & UCL Institute of Neurology, United Kingdom
                Author notes
                [* ]Corresponding author at: Institute of UCL Institute of Cognitive Neuroscience, Alexandra House, 17 Queen Square, London WC1N 3AR, United Kingdom. Tel.: +44 207 6791149. m.husain@ 123456ion.ucl.ac.uk
                Article
                NSY3130
                10.1016/j.neuropsychologia.2008.11.033
                2697316
                19138694
                e8927520-e5fe-43b3-8f6f-fd2b094d83d4
                © 2009 Elsevier Ltd.

                This document may be redistributed and reused, subject to certain conditions.

                History
                : 7 April 2008
                : 23 October 2008
                : 25 November 2008
                Categories
                Article

                Neurology
                hemispatial neglect,sustained attention,oddball,locus coeruleus,salience
                Neurology
                hemispatial neglect, sustained attention, oddball, locus coeruleus, salience

                Comments

                Comment on this article

                scite_
                0
                0
                0
                0
                Smart Citations
                0
                0
                0
                0
                Citing PublicationsSupportingMentioningContrasting
                View Citations

                See how this article has been cited at scite.ai

                scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.

                Similar content150

                Cited by130

                Most referenced authors952