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      Isolated aseptic loosening in total knee arthroplasty: a comprehensive 10-year review of partial vs. total component revisions

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          Abstract

          Background

          In total knee arthroplasty (TKA), isolated aseptic loosening (IAL) requires the replacement of prosthetic components, with ongoing debate regarding the effectiveness of partial component revision (PCR) compared to total component revision (TCR). This study aims to compare implant survival and surgical outcomes between PCR and TCR in the context of IAL.

          Methods

          This retrospective study analyzed data from 285 patients who underwent revision TKA for IAL between January 2000 and December 2013. After applying exclusion criteria, 112 patients were included in the analysis—60 undergoing TCR and 52 undergoing PCR.

          Results

          PCR was associated with shorter operative times and hospital stays compared to TCR, alongside significant differences in the choice of revision prostheses. Although the prosthesis failure rates were comparable between the groups (13.6% for TCR and 18.33% for PCR), significant risk factors for failure were identified, including a canal filling ratio (CFR) below 0.8 and a discrepancy over 0.2 between CFR views. However, no significant differences in overall survivorship were observed between the groups.

          Conclusions

          Both PCR and TCR provide similar survival rates and clinical outcomes for managing IAL in TKA. PCR provides advantages in terms of surgical efficiency and patient recovery, while reducing the need for more constrained prosthetic solutions. The study identifies CFR as a critical predictor of prosthesis failure, highlighting the importance of detailed preoperative planning and implant selection. These findings contribute valuable insights for improving revision strategies in IAL, enhancing surgical outcomes in TKA.

          Level of evidence

          III.

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          Most cited references26

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          Femoral Component Varus Malposition is Associated with Tibial Aseptic Loosening After TKA.

          The notion that neutral alignment is mandatory to assure long-term durability after TKA has been based mostly on short-film studies. However, this is challenged by recent long-film studies.
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            Patient-related risk factors leading to aseptic stem loosening in total hip arthroplasty: a case-control study of 5,035 patients.

            We hypothesized that certain patient characteristics have different effects on the risk of early stem loosening in total hip arthroplasty (THA). We therefore conducted a case-control study using register-database records with the aim of identifying patient-specific risk factors associated with radiographic signs of aseptic loosening of the femoral component in THA. Data were derived from a multinational European registry and were collected over a period of 25 years. 725 cases with radiographic signs of stem loosening were identified and matched to 4,310 controls without any signs of loosening. Matching criteria were type of implant, size of head, date of operation, center of primary intervention, and follow-up time. The risk factors analyzed were age at operation, sex, diagnosis and previous ipsilateral operations, height, weight, body mass index and mobility based on the Charnley classification. Women showed significantly lower risk of radiographic loosening than men (odds ratio (OR) 0.64). Age was also a strong factor: risk decreased by 1.8% for each additional year of age at the time of surgery. Height and weight were not associated with risk of loosening. A higher body mass index, however, increased the risk of stem loosening to a significant extent (OR 1.03) per additional unit of BMI. Charnley Class B, indicating restricted mobility, was associated with lower risk of loosening (OR 0.78). An increased activity level, as seen in younger patients and those with unrestricted mobility, is an important factor in the etiology of stem loosening. If combined with high BMI, the risk of stem loosening within 10 years is even higher. A younger person should not be denied the benefits of a total hip arthroplasty but must accept that the risk of future failure is increased.
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              Clinical & radiographic outcomes of cemented vs. diaphyseal engaging cementless stems in aseptic revision TKA.

              Modular revision systems have become standard in revision TKAs. However, the type of stem fixation remains controversial. The purpose of this study is to compare the incidence of failure between cemented and diaphyseal engaging cementless stems in aseptic revision TKAs. We performed a multicenter retrospective review of 82 revision TKAs performed for aseptic failure. Follow-up averaged 76 and 121 months for the cemented and cementless groups respectively. Re-revision and radiographic failure rates for both femoral and tibial stems were similar between groups. We found similar improvements in knee society scores between the groups. At midterm follow-up, we found no difference in failure rates between the groups. Both types of stem appear to provide reliable fixation and are viable options in revision TKAs.
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                Author and article information

                Contributors
                r52906154@cgmh.org.tw
                bighead1217@gmail.com
                Journal
                BMC Musculoskelet Disord
                BMC Musculoskelet Disord
                BMC Musculoskeletal Disorders
                BioMed Central (London )
                1471-2474
                12 October 2024
                12 October 2024
                2024
                : 25
                : 806
                Affiliations
                [1 ]Department of Orthopaedic Surgery, Chang Gung Memorial Hospital (CGMH), ( https://ror.org/02verss31) No. 5 Fu-Hsing Street, Kweishan, Taoyuan city, Taiwan
                [2 ]Bone and Joint Research Center, Chang Gung Memorial Hospital (CGMH), ( https://ror.org/02verss31) No. 5 Fu-Hsing Street, Kweishan, Taoyuan city, Taiwan
                [3 ]GRID grid.145695.a, ISNI 0000 0004 1798 0922, College of Medicine, , Chang Gung University (CGU), ; 259 Wen-Hwa 1st Road, Kweishan, Taoyuan city, Taiwan
                [4 ]Institute of Statistics, National Yang Ming Chiao Tung University, ( https://ror.org/00se2k293) 1001 University Road, Hsinchu, 300 Taiwan
                Article
                7925
                10.1186/s12891-024-07925-w
                11470593
                39395955
                e8835051-5efa-4754-9127-c0b013a27830
                © The Author(s) 2024

                Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

                History
                : 1 May 2024
                : 7 October 2024
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100005795, Chang Gung Memorial Hospital, Linkou;
                Award ID: CMRPG5M0121
                Categories
                Research
                Custom metadata
                © BioMed Central Ltd., part of Springer Nature 2024

                Orthopedics
                isolated aseptic loosening,partial component revision,total component revision
                Orthopedics
                isolated aseptic loosening, partial component revision, total component revision

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