Sesamol supplementation prevents systemic inflammation-induced memory impairment and amyloidogenesis via inhibition of nuclear factor kappaB.

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Abstract

The aim of the present study was to investigate the inhibitory effects of sesamol, a phenolic lignan from sesame, on the systemic inflammation-induced neuroinflammation and amyloidogenesis as well as memory impairment.

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Author and article information

Journal

Journal ID (iso-abbrev): Mol Nutr Food Res

Title: Molecular nutrition & food research

Publisher: Wiley-Blackwell

ISSN (Electronic): 1613-4133

ISSN (Print): 1613-4125

Publication date (Electronic): May 2017

Volume: 61

Issue: 5

Affiliations

[1 ] Laboratory of Functional Chemistry and Nutrition of Food, College of Food Science and Engineering, Northwest A&F University, Yangling, China.

Article

DOI: 10.1002/mnfr.201600734

PubMed ID: 27860258

SO-VID: e87f2d90-f7e3-409e-add3-0c518d197f41

History

Keywords: Amyloidogenesis,Lipopolysaccharide,Neuroinflammation,Nuclear factor kappaB,Sesamol

Data availability:

Keywords: Amyloidogenesis, Lipopolysaccharide, Neuroinflammation, Nuclear factor kappaB, Sesamol

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