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      EUS–guided gastroenterostomy for afferent loop syndrome treatment stent

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          Abstract

          Afferent loop syndrome is a known complication of pancreaticoduodenectomy. The incidence may be as high as 13%, and survival of 3 years or longer is the only factor associated with its development.[1] Surgical, percutaneous, and endoscopic treatments of afferent loop syndrome have been described, but such treatments are not always feasible. Successful treatment through EUS–guided hepaticogastrostomy has also been reported by our group.[2] We herein present a video case of EUS-guided gastroenterostomy for afferent loop syndrome treatment with SPAXUS® stent (Taewong Medical, Gyeonggi-do, South Korea). An 80-year-old man, who had undergone Whipple surgery in 2012 for pancreatic adenocarcinoma, was referred for abdominal pain and fever associated with bile duct and afferent loop dilation. A nodule of carcinomatosis localized in the gastrojejunal anastomosis, which was causing the obstruction, was punctured, and carcinoma relapse was histologically confirmed [Figures 1 and 2]. Figure 1 Nodule of carcinomatosis localized in the gastrojejunal anastomosis Figure 2 Nodule of carcinomatosis and dilated afferent loop Transgastric puncture of the dilated afferent loop was performed with a 10-Fr Cystotome™ (Cook Medical Ireland, Limrick, Ireland)). Contrast was injected for fluoroscopic viewing of limb and bile duct dilatation [Figure 3]. The incision was enlarged with the 10-Fr Cystotome after insertion of a 0.035-inch guidewire (G-FLEX®, Nivelles, Belgium). A 2-cm-long × 16-mm-diameter ASPAXUS® stent (TaeWoong Medical, Gyeonggi-do, South Korea) was deployed under fluoroscopic view. An 8-mm Hurricane dilatation balloon (Boston Scientific Corp, MA, USA) was then used to dilate the tract within the lumen of the NTI-S™ SPAXUS® stent (Taewong Medical, Gyeonggi-do, South Korea), and a 7-cm × 7-Fr pigtail stent was inserted within the stent to prevent migration [Figure 4]. Figure 3 Fluoroscopic view: Limb and bile duct dilatation Figure 4 Fluoroscopic view: 7-cm × 7-Fr pigtail stent within SPAXUS® stent No serious complication was reported after the procedure, except for abdominal pain, which was managed with analgesic. The patient was discharged 4 days after the procedure. The patient died 3 months after the procedure because of disease progression. EUS-guided treatment of afferent loop syndrome has been reported using transgastric plastic stent insertion,[3] metallic stent (NAGY and AXIOS),[4 5] and also hepaticogastrostomy,[2] as we have already mentioned. To our knowledge, this is the first reported case of treatment with the SPAXUS® stent. EUS-guided gastroenterostomy in this clinical case was performed safely and efficiently, but larger series is needed to evaluate the procedure. Patient informed consent The authors certify that they have obtained all appropriate patient consent forms. In the form the patient has given his consent for his images and other clinical information to be reported in the journal. The patient understands that his name and initial will not be published and due efforts will be made to conceal his identity, but anonymity cannot be guaranteed. Financial support and sponsorship This work was not supported by any funding sources, grants, or sponsorships. Conflicts of interest There are no conflicts of interest.

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          Afferent limb syndrome and delayed GI problems after pancreaticoduodenectomy for pancreatic cancer: single-center, 14-year experience.

          There are limited data on the incidence of afferent limb syndrome and other delayed GI problems in pancreatic cancer (PaC) patients, especially among long-term survivors (>2 years). To evaluate the incidence of afferent limb syndrome (chronic afferent limb obstruction resulting in pancreatobiliary obstruction) and delayed GI problems in PaC patients after pancreaticoduodenectomy (PD). Retrospective case series. Tertiary referral center. PaC patients treated with PD (N = 186) over a 14-year period (January 1995-October 2009). Endoscopic balloon dilation and stent placement, percutaneous biliary drainage. Incidence of afferent limb syndrome and delayed GI complications (marginal ulcers, radiation enteropathy, anastomotic strictures). Mean age was 63 ± 10 years; 55% of patients were male. Afferent limb syndrome was noted in 24 patients (13%). Median time to diagnosis was 1.2 years (range 0.03-12.3 years); obstruction was primarily caused by recurrent PaC (8 patients, 33%) and radiation enteropathy (9 patients, 38%). Afferent limb syndrome was more likely to develop in patients with 2 years or longer of follow-up (n = 71, [38%]) compared with patients with 2 years or less of follow-up, after controlling for age, sex, surgery type, and adjuvant treatment (adjusted odds ratio, 4.5; 95% CI, 1.8-11.7). Other delayed GI problems included radiation enteropathy (6%), marginal ulcers (5%), anastomotic strictures (4%), cholangitis/liver abscesses (5%), and GI bleeding (6%). Retrospective, single-center study. GI problems, including afferent limb syndrome, are relatively common in PaC patients after surgery and adjuvant therapy. Clinicians should recognize and effectively treat these delayed GI problems, especially in long-term survivors. Copyright © 2011 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.
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            Treatment of afferent limb syndrome: novel approach with endoscopic ultrasound-guided creation of a gastrojejunostomy fistula and placement of lumen-apposing stent.

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              A case of acute afferent loop syndrome treated by transgastric drainage with EUS.

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                Author and article information

                Journal
                Endosc Ultrasound
                Endosc Ultrasound
                EUS
                Endoscopic Ultrasound
                Medknow Publications & Media Pvt Ltd (India )
                2303-9027
                2226-7190
                Nov-Dec 2018
                12 July 2018
                : 7
                : 6
                : 418-419
                Affiliations
                [1]Division of Gastroenterology, Paoli-Calmettes Institute, Marseille, France
                Author notes
                Address for correspondence Dr. Dina Chaaro Benallal, Hospital Universitario Virgen Macarena, Seville, Spain. E-mail: d.chaaro@ 123456gmail.com
                Article
                EUS-7-418
                10.4103/eus.eus_41_17
                6289015
                30004036
                e7eb9c77-ee86-40cf-8066-0f4e0fefc9a0
                Copyright: © 2018 Spring Media Publishing Co. Ltd

                This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

                History
                : 12 January 2017
                : 22 May 2017
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