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      Developmental stability of general and specific factors of psychopathology from early childhood to adolescence: dynamic mutualism or p‐differentiation?

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          Abstract

          Background

          Recent research indicates that the best‐fitting structural model of psychopathology includes a general factor capturing comorbidity ( p) and several more specific, orthogonal factors. Little is known about the stability of these factors, although two opposing developmental processes have been proposed: dynamic mutualism suggests that symptom‐level interaction and reinforcement may lead to a strengthening of comorbidity ( p) over time, whereas p‐differentiation suggests a general vulnerability to psychopathology that gives way to increasingly distinct patterns of symptoms over time. In order to test both processes, we examine two forms of developmental stability from ages 2 to 14 years: strength (i.e., consistency in the amount of variance explained by general and specific factors) and phenotypic stability (i.e., homotypic and heterotypic continuity).

          Methods

          Data are from the NICHD Study of Early Child Care and Youth Development. Psychopathology symptoms were assessed nine times between ages 2 and 14 years ( n = 1,253) using the Child Behavior Checklist completed by mothers. Confirmatory bifactor modeling was used to test structural models of psychopathology at each age. Consistency in strength was examined by calculating the Explained Common Variance (ECV) and phenotypic stability was investigated with cross‐lagged modeling of the general and specific factors.

          Results

          Bifactor models fit the data well across this developmental period. ECV values were reasonably consistent across development, with the general factor accounting for the majority of shared variance (61%–71%). Evidence of both homotypic and heterotypic continuity emerged, with most heterotypic continuity involving the general factor, as it both predicted and was predicted by specific factors.

          Conclusions

          A bifactor model effectively captures psychopathological comorbidity from early childhood through adolescence. The longitudinal associations between the general and specific factors provide evidence for both the hypothesized processes ( dynamic mutualism and p‐differentiation) occurring through development.

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          Most cited references29

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          Comorbidity

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            Multidimensionality and Structural Coefficient Bias in Structural Equation Modeling

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              Empirically based assessment of the behavioral/emotional problems of 2- and 3- year-old children.

              The aim was to determine whether ratings of 2- and 3-year-olds could yield more differentiation among their behavioral/emotional problems than the internalizing-externalizing dichotomy found in previous studies. The 99-item Child Behavior Checklist for Ages 2-3 (CBCL/2-3) was designed to extend previously developed empirically based assessment procedures to 2-and 3-year-olds. Factor analyses of the CBCL/2-3 completed by parents of 398 2- and 3-year-olds yielded six syndromes having at least eight items loading greater than or equal to .30 and designated as Social Withdrawal, Depressed, Sleep Problems, Somatic Problems, Aggressive, and Destructive. Second-order analyses showed that the first two were related to a broad-band internalizing grouping, whereas the last two were related to a broad-band externalizing grouping. Scales for the six syndromes, two broad-band groupings, and total problem score were constructed from scores obtained by 273 children in a general population sample. Mean test-retest reliability r was .87, 1-year stability r was .69, 1-year predictive r with CBCL/4-16 scales at age 4 was .63, 2-year predictive r was .55, and 3-year predictive r was .49. Children referred for mental health services scored significantly higher than nonreferred children on all scales. A lack of significant r's with the Minnesota Child Development Inventory, Bayley, and McCarthy indicate that the CBCL/2-3 taps behavioral/emotional problems independently of the developmental variance tapped by these measures.
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                Author and article information

                Contributors
                emcelroy@liverpool.ac.uk
                Journal
                J Child Psychol Psychiatry
                J Child Psychol Psychiatry
                10.1111/(ISSN)1469-7610
                JCPP
                Journal of Child Psychology and Psychiatry, and Allied Disciplines
                John Wiley and Sons Inc. (Hoboken )
                0021-9630
                1469-7610
                02 December 2017
                June 2018
                : 59
                : 6 ( doiID: 10.1111/jcpp.2018.59.issue-6 )
                : 667-675
                Affiliations
                [ 1 ] Institute of Psychology Health and Society University of Liverpool Liverpool UK
                [ 2 ] Department of Human Ecology University of California Davis CA USA
                [ 3 ] Office of Medical Education University of New South Wales Sydney NSW Australia
                [ 4 ] Research Department of Clinical, Educational and Health Psychology University College London London UK
                Author notes
                [*] [* ] Correspondence

                Eoin McElroy, Institute of Psychology Health and Society, Eleanor Rathbone Building, Liverpool L69 3BX, UK; Email: emcelroy@ 123456liverpool.ac.uk

                Author information
                http://orcid.org/0000-0003-1847-8443
                http://orcid.org/0000-0002-5341-3461
                Article
                JCPP12849
                10.1111/jcpp.12849
                6001631
                29197107
                e73a0f9e-cdb7-4f9c-8a1b-79144bde1331
                © 2017 The Authors. Journal of Child Psychology and Psychiatry published by John Wiley & Sons Ltd on behalf of Association for Child and Adolescent Mental Health.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 27 October 2017
                Page count
                Figures: 2, Tables: 1, Pages: 9, Words: 6760
                Funding
                Funded by: Wellcome Trust
                Award ID: 204366/Z/16/Z
                Categories
                Original Article
                Original Articles
                Custom metadata
                2.0
                jcpp12849
                June 2018
                Converter:WILEY_ML3GV2_TO_NLMPMC version:version=5.4.1.1 mode:remove_FC converted:14.06.2018

                Clinical Psychology & Psychiatry
                comorbidity,continuity,developmental psychopathology,externalizing disorder,internalizing disorder

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