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      Metabolic syndrome update.

      1
      Trends in cardiovascular medicine
      Diabetes, Dyslipidemia, Hypertension, Metabolic syndrome, Nutrition, Obesity

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          Abstract

          The metabolic syndrome is a multiplex risk factor for atherosclerotic cardiovascular disease and type 2 diabetes. It is composed of atherogenic dyslipidemia, elevated blood pressure, insulin resistance and elevated glucose, a pro-thrombotic state, and a pro-inflammatory state. Excess energy intake and concomitant obesity are the major drivers of the syndrome. Lifestyle intervention can reverse metabolic risk factors, but at times, drug therapies or bariatric surgery may be required to control more overt risk factors.

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          Author and article information

          Journal
          Trends Cardiovasc. Med.
          Trends in cardiovascular medicine
          1873-2615
          1050-1738
          May 2016
          : 26
          : 4
          Affiliations
          [1 ] Department of Internal Medicine and Center for Human Nutrition, UT Southwestern Medical Center, Dallas, TX; Veterans Affairs Medical Center, Dallas, TX. Electronic address: scott.grundy@utsouthwestern.edu.
          Article
          S1050-1738(15)00249-2
          10.1016/j.tcm.2015.10.004
          26654259
          e58d9066-9348-4b95-918b-92db797ce78f
          Published by Elsevier Inc.
          History

          Diabetes,Dyslipidemia,Hypertension,Metabolic syndrome,Nutrition,Obesity

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