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      Aporte nutricional e desfechos em pacientes críticos no final da primeira semana na unidade de terapia intensiva Translated title: Nutritional support and outcomes in critically ill patients after one week in the intensive care unit

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          Abstract

          OBJETIVO: Avaliar a relação entre a oferta comparada às necessidades calóricas e proteicas no 7º dia de internação e desfechos de interesse em uma unidade de terapia intensiva. MÉTODOS: Estudo de coorte, retrospectivo, realizado na unidade de terapia intensiva, com 126 pacientes internados por >7 dias, que foram categorizados de acordo com a adequação da oferta energética e proteica administrada, em relação às necessidades. O Grupo Oferta Adequada >60% e o Grupo Suboferta <60% foram avaliados em relação ao tempo de internação, tempo livre de ventilação mecânica invasiva e mortalidade na unidade de terapia intensiva e hospitalar. RESULTADOS: Nutrição enteral foi utilizada em 95,6% dos 126 pacientes incluídos e iniciada 41 horas após a admissão na unidade de terapia intensiva. A adequação da oferta energética foi de 84% e, de proteínas, 72,5%. Não houve diferença entre os grupos oferta adequada e suboferta de energia em relação ao tempo de internação [16 (11-23) versus 15 (11-21) dias; p=0,862], tempo livre de ventilação mecânica invasiva [2 (0-7) versus 3 (0-6) dias; p=0,985], mortalidade na unidade de terapia intensiva [12 (41,4%) versus 38 (39,1%); p=0,831] e hospitalar [15 (51,7%) versus 44 (45,4%); p=0,348], respectivamente. Resultados semelhantes foram encontrados em relação à oferta proteica e ao tempo de internação [15 (12-21) versus 15 (11-21) dias; p=0,996], tempo livre de ventilação mecânica invasiva [2 (0-7) versus 3 (0-6) dias; p=0,846], mortalidade na unidade de terapia intensiva [15 (28,3%) versus 35 (47,9%); p=0,536)] e hospitalar [18 (52,9%) versus 41 (44,6%); p=0,262]. CONCLUSÃO: Não foi possível demonstrar que as ofertas energética e proteica, superior ou inferior a 60% das necessidades nutricionais, sejam divisores confiáveis, em termos de desfechos clínicos.

          Translated abstract

          OBJECTIVE: This study evaluated the relationship between nutritional intake and protein and caloric requirements and observed clinical outcomes on the 7th day of intensive care unit stay. METHODS: This was a retrospective cohort study of 126 patients who were admitted to the intensive care unit for >7 days. The patients were categorized according to the adequacy of energy and protein intake in relation to requirements (a >60% Adequate Intake Group and a <60% Inadequate Intake Group). The length of stay, ventilator free time and mortality in the intensive care unit and hospital were evaluated. RESULTS: Enteral nutrition was used in 95.6% of the 126 included patients, and nutrition was initiated 41 hours after admission to the intensive care unit. The adequacy of intake was 84% for energy and 72.5% for protein. No differences in the length of stay [16 (11-23) versus 15 (11-21) days, p=0.862], ventilator free time [2 (0-7) versus 3 (0-6) days, p=0.985] or mortality in the intensive care unit [12 (41.4%) versus 38 (39.1%), p=0.831] and hospital [15 (51.7%) versus 44 (45.4%), p=0.348] were observed between the adequate and inadequate energy intake groups, respectively. Similar results in protein intake and the length of hospital stay [15 (12-21) versus 15 (11-21) days, p=0.996], ventilator free time [2 (0-7) versus 3 (0-6) days, p=0.846], and mortality in the intensive care unit [15 (28.3%) versus 35 (47.9%), p=0.536)] and hospital [18 (52.9%) versus 41 (44.6%), p=0.262] were observed between groups. CONCLUSION: The results did not establish that energy and protein intakes of greater or less than 60% of nutritional requirements were reliable dividers of clinical outcomes.

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          Most cited references34

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          Screening for nutritional status in the elderly.

          A comprehensive assessment of nutritional status is a critically important component of any patient evaluation. Based upon clinical information, anthropometric data, and a small number of laboratory investigations, an accurate appraisal of nutritional status should be possible and an appropriate intervention plan can be developed. The actual approach depends on the particular problem discovered. These are discussed in detail elsewhere in this issue.
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            One-year outcomes in survivors of the acute respiratory distress syndrome.

            As more patients survive the acute respiratory distress syndrome, an understanding of the long-term outcomes of this condition is needed. We evaluated 109 survivors of the acute respiratory distress syndrome 3, 6, and 12 months after discharge from the intensive care unit. At each visit, patients were interviewed and underwent a physical examination, pulmonary-function testing, a six-minute-walk test, and a quality-of-life evaluation. Patients who survived the acute respiratory distress syndrome were young (median age, 45 years) and severely ill (median Acute Physiology, Age, and Chronic Health Evaluation score, 23) and had a long stay in the intensive care unit (median, 25 days). Patients had lost 18 percent of their base-line body weight by the time they were discharged from the intensive care unit and stated that muscle weakness and fatigue were the reasons for their functional limitation. Lung volume and spirometric measurements were normal by 6 months, but carbon monoxide diffusion capacity remained low throughout the 12-month follow-up. No patients required supplemental oxygen at 12 months, but 6 percent of patients had arterial oxygen saturation values below 88 percent during exercise. The median score for the physical role domain of the Medical Outcomes Study 36-item Short-Form General Health Survey (a health-related quality-of-life measure) increased from 0 at 3 months to 25 at 12 months (score in the normal population, 84). The distance walked in six minutes increased from a median of 281 m at 3 months to 422 m at 12 months; all values were lower than predicted. The absence of systemic corticosteroid treatment, the absence of illness acquired during the intensive care unit stay, and rapid resolution of lung injury and multiorgan dysfunction were associated with better functional status during the one-year follow-up. Survivors of the acute respiratory distress syndrome have persistent functional disability one year after discharge from the intensive care unit. Most patients have extrapulmonary conditions, with muscle wasting and weakness being most prominent. Copyright 2003 Massachusetts Medical Society
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              ESPEN Guidelines on Enteral Nutrition: Intensive care.

              Enteral nutrition (EN) via tube feeding is, today, the preferred way of feeding the critically ill patient and an important means of counteracting for the catabolic state induced by severe diseases. These guidelines are intended to give evidence-based recommendations for the use of EN in patients who have a complicated course during their ICU stay, focusing particularly on those who develop a severe inflammatory response, i.e. patients who have failure of at least one organ during their ICU stay. These guidelines were developed by an interdisciplinary expert group in accordance with officially accepted standards and are based on all relevant publications since 1985. They were discussed and accepted in a consensus conference. EN should be given to all ICU patients who are not expected to be taking a full oral diet within three days. It should have begun during the first 24h using a standard high-protein formula. During the acute and initial phases of critical illness an exogenous energy supply in excess of 20-25 kcal/kg BW/day should be avoided, whereas, during recovery, the aim should be to provide values of 25-30 total kcal/kg BW/day. Supplementary parenteral nutrition remains a reserve tool and should be given only to those patients who do not reach their target nutrient intake on EN alone. There is no general indication for immune-modulating formulae in patients with severe illness or sepsis and an APACHE II Score >15. Glutamine should be supplemented in patients suffering from burns or trauma.
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                Author and article information

                Journal
                rbti
                Revista Brasileira de Terapia Intensiva
                Rev. bras. ter. intensiva
                Associação de Medicina Intensiva Brasileira - AMIB (São Paulo, SP, Brazil )
                0103-507X
                1982-4335
                September 2012
                : 24
                : 3
                : 263-269
                Affiliations
                [01] orgnameUniversidade Federal do Rio Grande do Sul orgdiv1Hospital de Clínicas de Porto Alegre
                [03] Porto Alegre RS orgnameUniversidade Federal do Rio Grande do Sul orgdiv1Hospital de Clínicas de Porto Alegre orgdiv2Serviço de Medicina Intensiva Brasil
                [02] Porto Alegre RS orgnameUniversidade Federal do Rio Grande do Sul orgdiv1Hospital de Clínicas de Porto Alegre orgdiv2Serviço de Nutrição Brasil
                Article
                S0103-507X2012000300010 S0103-507X(12)02400310
                e418e873-57e9-4d29-9a0e-1849d7a07282

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                : 28 December 2011
                : 24 August 2012
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 34, Pages: 7
                Categories
                Artigos Originais - Pesquisa Clínica

                Respiração artificial,Necessidade energética,Intensive care units,Length of stay,Respiration, artificial,Mortality,Nutrition therapy,Unidades de terapia intensiva,Energy requirement,Terapia nutricional,Mortalidade,Tempo de internação

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