Reassessing the optimal volume for malignancy detection in serous fluid cytology.

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Abstract

The international system for reporting serous fluid cytopathology (TIS) recommends submitting at least 50-75 mL of serous fluid to decrease false-negative results. However, prior studies did not agree on specific volume requirements or consensus adequacy criteria. Our study aims to assess whether fluid volume affects the adequacy rate and to assess the minimum volume necessary for optimal adequacy in pleural and peritoneal fluids.

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Author and article information

Journal

Journal ID (iso-abbrev): Cancer Cytopathol

Title: Cancer cytopathology

Publisher: Wiley

ISSN (Electronic): 1934-6638

ISSN (Print): 1934-662X

Publication date (Electronic): Jul 2022

Volume: 130

Issue: 7

Affiliations

[1 ] Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

[2 ] Department of Pathology and Cell Biology, Columbia University, New York, New York.

[3 ] Department of Biostatistics, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania.

Article

DOI: 10.1002/cncy.22577

PubMed ID: 35468659

SO-VID: e3e1173a-d89f-4965-9c22-8dd9a8e24425

History

Keywords: pleural effusion,malignant,ascitic fluid,adequate volume,adequacy,thoracentesis

Data availability:

Keywords: pleural effusion, malignant, ascitic fluid, adequate volume, adequacy, thoracentesis

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