Delayed manipulation after collagenase clostridium histolyticum injection for Dupuytren contracture.

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Abstract

Collagenase clostridium histolyticum (CCH) injection for Dupuytren contracture was approved in the USA in 2010. Current FDA guidelines stipulate that finger manipulation occurs the day following injection. To investigate the safety and efficacy of delaying manipulation to 2 or 4 days following CCH injection, we conducted a prospective, randomized trial at two sites.

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Author and article information

Journal

Journal ID (iso-abbrev): Hand (N Y)

Title: Hand (New York, N.Y.)

Publisher: Springer Nature

ISSN: 1558-9447

ISSN (Print): 1558-9447

Publication date (Electronic): Sep 2015

Volume: 10

Issue: 3

Affiliations

[1 ] Indiana Hand to Shoulder Center, 8501 Harcourt Rd, Indianapolis, IN 46260 USA.

[2 ] Department of Orthopaedics, Stony Brook University Medical Center, Stony Brook, NY USA.

Article

Publisher Item ID: 9714

DOI: 10.1007/s11552-014-9714-y

PMC ID: 4551642

PubMed ID: 26330801

SO-VID: e37e6b17-8229-4303-bbae-daef09a0139e

History

Keywords: Collagenase clostridium histolyticum,Delayed finger manipulation,Dupuytren contracture,Safety

Data availability:

Keywords: Collagenase clostridium histolyticum, Delayed finger manipulation, Dupuytren contracture, Safety

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