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      Multiple Sclerosis Patients Knowledge in Saudi Arabia

      brief-report

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          Abstract

          Objectives:

          To assess Multiple Sclerosis (MS) patients’ knowledge in Saudi Arabia (SA) and in which aspect of the disease do patient need more awareness.

          Methods:

          A cross-sectional web-based survey has been conducted between June and August 2017. It consisted of 2 parts: sociodemographic and 23 multiple choice questions chosen from the previously validated MS Knowledge Questionnaire (MSKQ). The survey has been sent to 500 MS patients.

          Results:

          A total of 218 MS patients filled the questionnaire where only 200 included in the study. Female MS patient represents 66% of all the participants. More than half of the patients had achieved their bachelor degree. The total mean of the correct answer for both male and female found to be 58.98%(±SD 15.06%). Most patients were aware that MS is a disease of central nervous system (93%), autoimmune disease (79%), not contagious (90.5%), or inherited (64.5%). However, few patients were aware that there is no single test to diagnose MS (28.5%), and intravenous injection of contrast during MRI reveals new lesions (18.5%). Only (37%) knew what is “Relapsing–remitting”MS. The MS knowledge is positively correlated with the educational level.

          Conclusion:

          Patients with MS in SA have less knowledge in the disease’s types, workups, and treatment efficacy. While in contrast, they have more awareness of the disease’s pathophysiology. Patient’s awareness programs should aid more knowledge among MS patients in SA.

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          Most cited references14

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          Environmental risk factors for multiple sclerosis. Part I: the role of infection.

          Although genetic susceptibility explains the clustering of multiple sclerosis (MS) cases within families and the sharp decline in risk with increasing genetic distance, it cannot fully explain the geographic variations in MS frequency and the changes in risk that occur with migration. Epidemiological data provide some support for the "hygiene hypothesis," but with the additional proviso for a key role of Epstein-Barr virus (EBV) in determining MS risk. We show that whereas EBV stands out as the only infectious agent that can explain many of the key features of MS epidemiology, by itself the link between EBV and MS cannot explain the decline in risk among migrants from high to low MS prevalence areas. This decline implies that either EBV strains in low-risk areas have less propensity to cause MS, or that other infectious or noninfectious factors modify the host response to EBV or otherwise contribute to determine MS risk. The role of infectious factors is discussed here; in a companion article, we will examine the possible role of noninfectious factors and provide evidence that high levels of vitamin D may have a protective role, particularly during adolescence. The primary purpose of these reviews is to identify clues to the causes of MS and to evaluate the possibility of primary prevention.
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            Multiple sclerosis review.

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              • Article: not found

              Genetics of multiple sclerosis.

              Multiple sclerosis (MS) is probably aetiologically heterogeneous. Systematic genetic epidemiological and molecular genetic studies have provided important insights. Both genetic and non-genetic (environment, stochastic) factors may be involved in susceptibility as well as outcome, but we have yet to understand their relative roles. Any environmental factor is likely to be ubiquitous and act on a population-basis rather than within the family microenvironment. Taken together, the results of genome screening studies provide strong evidence for exclusion of a major locus in MS. There are, however, many genes that seem to be associated with MS. These include, but are in no way limited to, HLA classes I and II, T-cell receptor beta, CTLA4, ICAM1, and SH2D2A. The future of MS genetics, as for most common complex disorders, will be dependent on the resources available, ranging from biological samples and comprehensive databases of clinical and epidemiological information to the development of new technologies and statistical methods.
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                Author and article information

                Journal
                Neurosciences (Riyadh)
                nsj
                nsj
                Neurosciences
                Neurosciences
                Riyadh : Armed Forces Hospital
                1319-6138
                1319-6138
                October 2019
                : 24
                : 4
                : 327-331
                Affiliations
                [1] From the Department of Medicine (Abulaban), King Abdulaziz Medical city, National Guard Health Affairs, Riyadh, and from College of Medicine (Altowairqi, Altowairqi, Almutairi, Altalhi, Alotaibi, Alabbadi), Taif University, Taif, Kingdom of Saudi Arabia.
                Author notes
                Address correspondence and reprint requests to: Dr. Ahmad Abulaban, Division of Neurology, Department of Medicine, King Saud bin-Abdulaziz University for Health Sciences, King Abdulaziz Medical City National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia. E-mail: neuroahmad@ 123456yahoo.com , abulabanah@ 123456ngha.med.sa ORCID: https://orcid.org/0000-0002-2508-9852
                Article
                Neurosciences-24-327
                10.17712/nsj.2019.4.20190031
                8015547
                31872816
                e353f1b5-e29e-47f9-8832-eec0f65dcd85
                Copyright: © Neurosciences

                Neurosciences is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

                History
                : 01 April 2019
                : 27 August 2019
                Categories
                Brief Communication

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