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      Mercury release of amalgams with various silver contents after exposure to bleaching agent

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          Abstract

          Background. Since it is possible for carbamide peroxide (CP) bleaching agent to contact old amalgam restorations, the present in vitro study evaluated the amount of dissolved mercury released from amalgam restorations with various percent-ages of silver content subsequent to the use of 15% CP.

          Methods. Thirty ANA 2000 amalgam disks with 43.1% silver content and thirty ANA 70 amalgam disks with 69.3% silver content were prepared. In each group, 15 samples were randomly placed in glass tubes containing 15% CP (as experimental groups) and the remaining 15 samples were placed in buffered phosphate solution (as control groups) with the same 3-mL volume for 48 hours. Subsequently, the amount of mercury dissolved in each test tube was measured using Mercury Analyzing System (Cold Vapor Atomic Absorption, MASLO, Shimadzu, Japan). Data was analyzed with two-way ANOVA and a post hoc Tukey test. (α = 0.05).

          Results. The amount of mercury released after exposure to CP was significantly higher than that released after exposure to buffered phosphate (P < 0.001). In addition, the amount of mercury released from dental amalgam with a silver content of 43% was significantly higher than that released from dental amalgam with a silver content of 69% (P < 0.001).

          Conclusion. The amount of mercury release is inversely proportional to the silver content of dental amalgam.

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          Most cited references33

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          History, safety, and effectiveness of current bleaching techniques and applications of the nightguard vital bleaching technique.

          B. Haywood (1992)
          This article reviews the literature on the use of hydrogen peroxide in three professionally administered bleaching techniques from historical, technique, and safety viewpoints. Safety over time, absolute safety, and relative safety of nonvital bleaching, in-office vital bleaching, nightguard vital bleaching, and over-the-counter bleaching kits are compared. The advantages and disadvantages of different bleaching options, as well as indications for individual or combined use of the techniques, are discussed. In addition, specific indications for the use of the nightguard vital bleaching technique are presented.
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            High-Field MRI and Mercury Release from Dental Amalgam Fillings

            Mercury is among the most toxic nonradioactive elements which may cause toxicity even at low doses. Some studies showed release of mercury from dental amalgam fillings in individuals who used mobile phone. This study was conducted to assess the effect of high-field MRI on mercury release from dental amalgam filling. We studied two groups of students with identical tooth decays requiring a similar pattern of restorative dentistry. They were exposed to a magnetic flux density of 1.5 T produced by a MRI machine. 16 otherwise healthy students with identical dental decay participated in this study. They underwent similar restorative dentistry procedures and randomly divided into two groups of MRI-exposed and control arms. Urinary concentrations of mercury in the control subjects were measured before (hour 0) and 48 and 72 hrs after amalgam restoration, using cold vapor atomic absorption spectrometry. Urinary concentrations of mercury in exposed individuals were determined before (hour 0), and 24, 48, 72 and 96 hrs after amalgam restoration. Unlike control subjects, they underwent conventional brain MRI (15 min, 99 slices), 24 hrs after amalgam restoration. The mean±SD urinary mercury levels in MRI-exposed individuals increased linearly from a baseline value of 20.70±17.96 to 24.83±22.91 µg/L 72 hrs after MRI. In the control group, the concentration decreased linearly from 20.70±19.77 to 16.14±20.05 µg/L. The difference between urinary mercury in the exposed and control group, 72 hrs after MRI (96 h after restoration),was significant (p=0.046). These findings provide further support for the noxious effect of MRI (exposure to strong magnetic field)and release of mercury from dental amalgam fillings.
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              New science challenges old notion that mercury dental amalgam is safe

              Mercury dental amalgam has a long history of ostensibly safe use despite its continuous release of mercury vapor. Two key studies known as the Children’s Amalgam Trials are widely cited as evidence of safety. However, four recent reanalyses of one of these trials now suggest harm, particularly to boys with common genetic variants. These and other studies suggest that susceptibility to mercury toxicity differs among individuals based on multiple genes, not all of which have been identified. These studies further suggest that the levels of exposure to mercury vapor from dental amalgams may be unsafe for certain subpopulations. Moreover, a simple comparison of typical exposures versus regulatory safety standards suggests that many people receive unsafe exposures. Chronic mercury toxicity is especially insidious because symptoms are variable and nonspecific, diagnostic tests are often misunderstood, and treatments are speculative at best. Throughout the world, efforts are underway to phase down or eliminate the use of mercury dental amalgam.
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                Author and article information

                Journal
                J Dent Res Dent Clin Dent Prospects
                J Dent Res Dent Clin Dent Prospects
                J Dent Res Dent Clin Dent Prospects
                JODDD
                TBZMED
                Journal of Dental Research, Dental Clinics, Dental Prospects
                Tabriz University of Medical Sciences
                2008-210X
                2008-2118
                Spring 2016
                15 June 2016
                : 10
                : 2
                : 118-123
                Affiliations
                1Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
                2Assistant Professor, Department of Operative Dentistry, Dental Faculty, Tabriz University of Medical Sciences, Tabriz, Iran
                3Professor, Department of Operative Dentistry, Dental Faculty, Tabriz University of Medical Sciences, Tabriz, Iran
                4Assistant Professor, Department of Oral Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
                5Assistant Professor, Department of Endodontics, Alborz University of Medical Sciences, Karaj, Iran
                Author notes
                [* ]Corresponding Author;E-mail: mahmoudbahari@ 123456ymail.com
                Article
                10.15171/joddd.2016.019
                4946001
                27429729
                e2a05326-7c4b-4cc7-b033-37df9ce6c1e3
                © 2016 Bahari et al.

                This is an Open Access article published and distributed by Tabriz University of Medical Sciences under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 19 July 2013
                : 07 March 2016
                Categories
                Original Article

                Dentistry
                carbamide peroxide,mercury,silver mercury amalgam,tooth bleaching
                Dentistry
                carbamide peroxide, mercury, silver mercury amalgam, tooth bleaching

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