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      Global infectious disease early warning models: An updated review and lessons from the COVID-19 pandemic

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          Abstract

          An early warning model for infectious diseases is a crucial tool for timely monitoring, prevention, and control of disease outbreaks. The integration of diverse multi-source data using big data and artificial intelligence techniques has emerged as a key approach in advancing these early warning models. This paper presents a comprehensive review of widely utilized early warning models for infectious diseases around the globe. Unlike previous review studies, this review encompasses newly developed approaches such as the combined model and Hawkes model after the COVID-19 pandemic, providing a thorough evaluation of their current application status and development prospects for the first time. These models not only rely on conventional surveillance data but also incorporate information from various sources. We aim to provide valuable insights for enhancing global infectious disease surveillance and early warning systems, as well as informing future research in this field, by summarizing the underlying modeling concepts, algorithms, and application scenarios of each model.

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            Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2)

            Estimation of the prevalence and contagiousness of undocumented novel coronavirus (SARS-CoV2) infections is critical for understanding the overall prevalence and pandemic potential of this disease. Here we use observations of reported infection within China, in conjunction with mobility data, a networked dynamic metapopulation model and Bayesian inference, to infer critical epidemiological characteristics associated with SARS-CoV2, including the fraction of undocumented infections and their contagiousness. We estimate 86% of all infections were undocumented (95% CI: [82%–90%]) prior to 23 January 2020 travel restrictions. Per person, the transmission rate of undocumented infections was 55% of documented infections ([46%–62%]), yet, due to their greater numbers, undocumented infections were the infection source for 79% of documented cases. These findings explain the rapid geographic spread of SARS-CoV2 and indicate containment of this virus will be particularly challenging.
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              Machine learning: Trends, perspectives, and prospects.

              Machine learning addresses the question of how to build computers that improve automatically through experience. It is one of today's most rapidly growing technical fields, lying at the intersection of computer science and statistics, and at the core of artificial intelligence and data science. Recent progress in machine learning has been driven both by the development of new learning algorithms and theory and by the ongoing explosion in the availability of online data and low-cost computation. The adoption of data-intensive machine-learning methods can be found throughout science, technology and commerce, leading to more evidence-based decision-making across many walks of life, including health care, manufacturing, education, financial modeling, policing, and marketing.
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                Author and article information

                Contributors
                Journal
                Infect Dis Model
                Infect Dis Model
                Infectious Disease Modelling
                KeAi Publishing
                2468-2152
                2468-0427
                03 December 2024
                June 2025
                03 December 2024
                : 10
                : 2
                : 410-422
                Affiliations
                [a ]Department of Epidemiology and Biostatistics, School of Public Health, Peking University, 38 Xueyuan Road, Beijing, 100191, China
                [b ]Peking University Center for Public Health and Epidemic Preparedness & Response, Peking University, 38 Xueyuan Road, Beijing, 100191, China
                [c ]Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, China
                Author notes
                [* ]Corresponding author. Peking University Center for Public Health and Epidemic Preparedness & Response, Peking University, 38 Xueyuan Road, Beijing, 100191, China. haoyt@ 123456bjmu.edu.cn
                Article
                S2468-0427(24)00127-1
                10.1016/j.idm.2024.12.001
                11731462
                39816751
                e221262f-a802-4498-bf90-6996ee8a7087
                © 2024 The Authors

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                : 14 March 2024
                : 29 August 2024
                : 1 December 2024
                Categories
                Article

                infectious disease,early warning model,combined model,hawkes model

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