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      International Journal of Nanomedicine (submit here)

      This international, peer-reviewed Open Access journal by Dove Medical Press focuses on the application of nanotechnology in diagnostics, therapeutics, and drug delivery systems throughout the biomedical field. Sign up for email alerts here.

      105,621 Monthly downloads/views I 7.033 Impact Factor I 10.9 CiteScore I 1.22 Source Normalized Impact per Paper (SNIP) I 1.032 Scimago Journal & Country Rank (SJR)

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      Green nanotechnology: a review on green synthesis of silver nanoparticles — an ecofriendly approach

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          Abstract

          Background: Nanotechnology explores a variety of promising approaches in the area of material sciences on a molecular level, and silver nanoparticles (AgNPs) are of leading interest in the present scenario. This review is a comprehensive contribution in the field of green synthesis, characterization, and biological activities of AgNPs using different biological sources.

          Methods: Biosynthesis of AgNPs can be accomplished by physical, chemical, and green synthesis; however, synthesis via biological precursors has shown remarkable outcomes. In available reported data, these entities are used as reducing agents where the synthesized NPs are characterized by ultraviolet-visible and Fourier-transform infrared spectra and X-ray diffraction, scanning electron microscopy, and transmission electron microscopy.

          Results: Modulation of metals to a nanoscale drastically changes their chemical, physical, and optical properties, and is exploited further via antibacterial, antifungal, anticancer, antioxidant, and cardioprotective activities. Results showed excellent growth inhibition of the microorganism.

          Conclusion: Novel outcomes of green synthesis in the field of nanotechnology are appreciable where the synthesis and design of NPs have proven potential outcomes in diverse fields. The study of green synthesis can be extended to conduct the in silco and in vitro research to confirm these findings.

          Most cited references199

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          Nanoparticles: Properties, applications and toxicities

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            Does the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle? A study of the Gram-negative bacterium Escherichia coli.

            In this work we investigated the antibacterial properties of differently shaped silver nanoparticles against the gram-negative bacterium Escherichia coli, both in liquid systems and on agar plates. Energy-filtering transmission electron microscopy images revealed considerable changes in the cell membranes upon treatment, resulting in cell death. Truncated triangular silver nanoplates with a {111} lattice plane as the basal plane displayed the strongest biocidal action, compared with spherical and rod-shaped nanoparticles and with Ag(+) (in the form of AgNO(3)). It is proposed that nanoscale size and the presence of a {111} plane combine to promote this biocidal property. To our knowledge, this is the first comparative study on the bactericidal properties of silver nanoparticles of different shapes, and our results demonstrate that silver nanoparticles undergo a shape-dependent interaction with the gram-negative organism E. coli.
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              Core/shell nanoparticles: classes, properties, synthesis mechanisms, characterization, and applications.

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                Author and article information

                Journal
                Int J Nanomedicine
                Int J Nanomedicine
                IJN
                intjnano
                International Journal of Nanomedicine
                Dove
                1176-9114
                1178-2013
                10 July 2019
                2019
                : 14
                : 5087-5107
                Affiliations
                [1 ]Department of Chemistry, Islamia College University , Peshawar 25120, Pakistan
                [2 ]Department of Chemistry, Government Girls Degree College , Peshawar, Pakistan
                [3 ]Department of Chemistry, Kohat University of Science and Technology , Kohat, Pakistan
                [4 ]Institute of Chemical Sciences, University of Swat , Swat, 19201, Pakistan
                [5 ]Department of Chemistry, University of Kotli 11100 , Azad Jammu and Kashmir, Pakistan
                Author notes
                Correspondence: Shabir AhmadDepartment of Chemistry, Islamia College University , Peshawar25120, PakistanTel +92 345 307 3759Email shabir.ahmad@ 123456icp.edu.pk
                Article
                200254
                10.2147/IJN.S200254
                6636611
                31371949
                e104d6d0-a8ef-4dfa-b704-a99f67dcb1c2
                © 2019 Ahmad et al.

                This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License ( http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms ( https://www.dovepress.com/terms.php).

                History
                : 05 January 2019
                : 26 March 2019
                Page count
                Figures: 2, Tables: 8, References: 250, Pages: 21
                Categories
                Review

                Molecular medicine
                green synthesis,plant mediated synthesis,silver bioactivity,microorganism
                Molecular medicine
                green synthesis, plant mediated synthesis, silver bioactivity, microorganism

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