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      La hiperreactividad cardiovascular y su asociación con factores de riesgo cardiovasculares Translated title: Cardiovascular Hyperreactivity and its Association with Cardiovascular Risk Factors

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          Abstract

          Fundamento: diversos estudios demuestran una estrecha relación entre el fenómeno de hiperreactividad cardiovascular y los factores de riesgo cardiovasculares, sin embargo, sigue siendo pertinente el aporte de nuevas evidencias que así lo corroboren. Objetivo: determinar la asociación entre la reactividad cardiovascular, en los individuos normotensos, y los factores de riesgo cardiovasculares. Métodos: se realizó un estudio descriptivo correlacional de corte transversal. El universo estuvo conformado por la población entre 15 y 74 años del área urbana del municipio Cienfuegos, la muestra fue de 644 personas evaluadas en el año 2010. Se consideraron como variables: sexo, color de la piel, edad, talla, peso, índice de masa corporal, cintura abdominal, triglicéridos, colesterol, HDL colesterol y glucemia en ayunas. Se calculó el Chi cuadrado y la razón de prevalencia con un intervalo de confianza del 95 %. Resultados: la prevalencia de hiperreactividad cardiovascular fue de 42,3 %. Se observó una razón de prevalencia de 51,3 % en los hombres y 36,8 % en las mujeres, sobrepasó el 65 % en los individuos con más de 64 años. Fue aumentando a medida que se incrementaba la edad, el mayor el porcentaje de hiperreactivos en obesos y sobrepesos, también fueron significativos los niveles de triglicéridos relacionados con la hiperreactividad cardiovascular. Conclusiones: existe asociación entre la hiperreactividad cardiovascular y los factores de riesgo cardiovasculares como: obesidad, hipertrigliceridemia e hipercolesterolemia en los individuos normotensos, situación que se mantiene aún en los individuos no obesos.

          Translated abstract

          Background: several studies show a relationship between cardiovascular hyperreactivity and cardiovascular risk factors. However, finding new evidence to corroborate. Objective: to determine the association between cardiovascular reactivity and cardiovascular risk factors in normotensive individuals. Methods: a cross-sectional, correlational study was conducted in a universe composed of the population aged 15 to 74 years in the urban area of Cienfuegos municipality. The sample included 644 people studied in 2010. The variables analyzed were: sex, skin color, age, height, weight, body mass index, waist circumference, triglycerides, cholesterol, HDL cholesterol and fasting blood glucose. Chi-square and prevalence ratio with a 95 % confidence interval were calculated. Results: the prevalence of cardiovascular hyperreactivity was 42.3 %. A prevalence ratio of 51.3 % in men and 36.8 % in women was observed and it exceeded 65 % in individuals older than 64 years. It increased with age. Highest percentage of hyperreactivity was found in obese and overweight individuals. Triglyceride levels associated with cardiovascular hyperreactivity were also significant. Conclusions: there is an association between cardiovascular hyperreactivity and cardiovascular risk factors such as obesity, hypertriglyceridemia and hypercholesterolemia in normotensive individuals, a situation still observed in non-obese individuals.

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          Most cited references39

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          General and abdominal adiposity and risk of death in Europe.

          Previous studies have relied predominantly on the body-mass index (BMI, the weight in kilograms divided by the square of the height in meters) to assess the association of adiposity with the risk of death, but few have examined whether the distribution of body fat contributes to the prediction of death. We examined the association of BMI, waist circumference, and waist-to-hip ratio with the risk of death among 359,387 participants from nine countries in the European Prospective Investigation into Cancer and Nutrition (EPIC). We used a Cox regression analysis, with age as the time variable, and stratified the models according to study center and age at recruitment, with further adjustment for educational level, smoking status, alcohol consumption, physical activity, and height. During a mean follow-up of 9.7 years, 14,723 participants died. The lowest risks of death related to BMI were observed at a BMI of 25.3 for men and 24.3 for women. After adjustment for BMI, waist circumference and waist-to-hip ratio were strongly associated with the risk of death. Relative risks among men and women in the highest quintile of waist circumference were 2.05 (95% confidence interval [CI], 1.80 to 2.33) and 1.78 (95% CI, 1.56 to 2.04), respectively, and in the highest quintile of waist-to-hip ratio, the relative risks were 1.68 (95% CI, 1.53 to 1.84) and 1.51 (95% CI, 1.37 to 1.66), respectively. BMI remained significantly associated with the risk of death in models that included waist circumference or waist-to-hip ratio (P<0.001). These data suggest that both general adiposity and abdominal adiposity are associated with the risk of death and support the use of waist circumference or waist-to-hip ratio in addition to BMI in assessing the risk of death. 2008 Massachusetts Medical Society
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            Anuario estadístico de salud 2014

            (2014)
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              Chronic life stress, cardiovascular reactivity, and subclinical cardiovascular disease in adolescents.

              To examine cross-sectional and longitudinal relationships between chronic life stress, cardiovascular reactivity, and a marker of subclinical cardiovascular disease in a multiethnic sample of adolescents. Participants were 158 healthy adolescents who completed self-report measures of chronic negative life stress as well as assessments of heart rate and blood pressure reactivity to acute laboratory stressors at two time points, approximately 3.3 years apart. At Time 2, intima-media thickness (IMT), a measure of subclinical atherosclerosis, was also measured. In hierarchical regression models adjusting for demographic variables and body mass index, chronic negative life stress at Time 2 was concurrently associated with greater diastolic blood pressure (DBP) reactivity to stress (beta = 0.18, p = .016), but neither chronic stress nor cardiovascular reactivity was associated concurrently with IMT. Increasing life stress from Time 1 to Time 2 was accompanied by increasing cardiovascular reactivity (beta = 0.14-0.20, p < .05), and increasing DBP reactivity over time was also associated with IMT (beta = 0.24, p = .03), although increasing chronic life stress was not directly related to IMT. Adolescents exposed to chronic, negative stressors that worsen over time may show heightened cardiovascular reactivity that puts them at risk for subclinical atherosclerosis.
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                Author and article information

                Journal
                rf
                Revista Finlay
                Rev. Finlay
                Universidad de Ciencias Médicas de Cienfuegos. Centro Provincial de información de Ciencias Médicas (Cienfuegos, , Cuba )
                2221-2434
                December 2015
                : 5
                : 4
                : 228-241
                Affiliations
                [01] Cienfuegos Cienfuegos orgnameUniversidad de Ciencias Médicas Cuba
                Article
                S2221-24342015000400003 S2221-2434(15)00500403
                e0c23402-a2c2-4ba1-ad36-eaa25f3ad21f

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 15 July 2015
                : 14 December 2015
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 39, Pages: 14
                Product

                SciELO Cuba

                Categories
                ARTÍCULOS ORIGINALES

                frecuencia cardiaca,mujeres,anciano,factores de riesgo,enfermedades cardiovasculares,women,aged,risk factors,cardiovascular diseases,heart rate

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