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      Effect of Laparoscopic vs Open Distal Gastrectomy on 3-Year Disease-Free Survival in Patients With Locally Advanced Gastric Cancer : The CLASS-01 Randomized Clinical Trial

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          Abstract

          Laparoscopic distal gastrectomy is accepted as a more effective approach to conventional open distal gastrectomy for early-stage gastric cancer. However, efficacy for locally advanced gastric cancer remains uncertain.

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          Author and article information

          Journal
          JAMA
          JAMA
          American Medical Association (AMA)
          0098-7484
          May 28 2019
          May 28 2019
          : 321
          : 20
          : 1983
          Affiliations
          [1 ]Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China
          [2 ]Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China
          [3 ]Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China
          [4 ]Key laboratory of Carcinogenesis and Translational Research, Ministry of Education, Gastrointestinal Cancer Center, Peking University Cancer Hospital and Institute, Beijing, China
          [5 ]Department of Gastrointestinal Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
          [6 ]Department of Gastrointestinal Surgery & Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China
          [7 ]Department of Gastrointestinal Surgery, the Cancer Hospital of Harbin Medical University, Harbin, China
          [8 ]Department of Gastrointestinal Surgery, the First Hospital, Jilin University, Changchun, China
          [9 ]Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
          [10 ]Department of General Surgery, Tangdu Hospital, Fourth Military Medical University, Xi’an, China
          [11 ]Department of Gastrointestinal Surgery, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
          [12 ]Department of Gastrointestinal Oncological Surgery, Fujian Provincial Cancer Hospital, Fuzhou, China
          [13 ]Department of Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
          [14 ]Department of General Surgery, General Hospital of PLA, Beijing, China
          [15 ]Department of Biostatistics, School of Public Health, Southern Medical University, Guangzhou, China
          Article
          10.1001/jama.2019.5359
          6547120
          31135850
          dfdad4ca-ca0a-4468-9ccc-2090a101cbb7
          © 2019
          History

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