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      Poultry feed contamination and its potential hazards on human health

      Biomedical Letters
      The Science Publishers

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          Abstract

          The poultry farm industry is growing quickly and tremendously contributing to meeting the increasing protein demand of the rapidly growing population through eggs and meat supplementation. It is a good and cheap source of low cholesterol and high protein meat and provides essential amino acids, vitamins and minerals. The poultry industry is big and developing worldwide. Because of the tremendous commercialization of poultry farms and the increased number of birds in poultry farms, there was a need to prepare poultry feed on an industrial scale. Because of industrialization and increasing environmental pollution, there are much higher chances that poultry feed may get contaminated with some toxic compounds during the process of preparation. Hazards associated with animal feed can be chemical, biological, or physical. Contamination of poultry feed may occur during handling, storage and transportation, or it may result from accidental or deliberate. Risk management should be based upon prevention rather than reaction after detection of the problem. Food safety hazards should be taken seriously to control side adverse effects on animals and humans. So, governments should take strict measures to avoid any toxic contamination hazardous to human health.

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          Most cited references70

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          Chemical Pesticides and Human Health: The Urgent Need for a New Concept in Agriculture

          The industrialization of the agricultural sector has increased the chemical burden on natural ecosystems. Pesticides are agrochemicals used in agricultural lands, public health programs, and urban green areas in order to protect plants and humans from various diseases. However, due to their known ability to cause a large number of negative health and environmental effects, their side effects can be an important environmental health risk factor. The urgent need for a more sustainable and ecological approach has produced many innovative ideas, among them agriculture reforms and food production implementing sustainable practice evolving to food sovereignty. It is more obvious than ever that the society needs the implementation of a new agricultural concept regarding food production, which is safer for man and the environment, and to this end, steps such as the declaration of Nyéléni have been taken.
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            Arsenic exposure and toxicology: a historical perspective.

            The metalloid arsenic is a natural environmental contaminant to which humans are routinely exposed in food, water, air, and soil. Arsenic has a long history of use as a homicidal agent, but in the past 100 years arsenic, has been used as a pesticide, a chemotherapeutic agent and a constituent of consumer products. In some areas of the world, high levels of arsenic are naturally present in drinking water and are a toxicological concern. There are several structural forms and oxidation states of arsenic because it forms alloys with metals and covalent bonds with hydrogen, oxygen, carbon, and other elements. Environmentally relevant forms of arsenic are inorganic and organic existing in the trivalent or pentavalent state. Metabolism of arsenic, catalyzed by arsenic (+3 oxidation state) methyltransferase, is a sequential process of reduction from pentavalency to trivalency followed by oxidative methylation back to pentavalency. Trivalent arsenic is generally more toxicologically potent than pentavalent arsenic. Acute effects of arsenic range from gastrointestinal distress to death. Depending on the dose, chronic arsenic exposure may affect several major organ systems. A major concern of ingested arsenic is cancer, primarily of skin, bladder, and lung. The mode of action of arsenic for its disease endpoints is currently under study. Two key areas are the interaction of trivalent arsenicals with sulfur in proteins and the ability of arsenic to generate oxidative stress. With advances in technology and the recent development of animal models for arsenic carcinogenicity, understanding of the toxicology of arsenic will continue to improve.
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              Aflatoxin B1 in Affecting Broiler’s Performance, Immunity, and Gastrointestinal Tract: A Review of History and Contemporary Issues

              Aflatoxin B1 is a common contaminant of poultry feeds in tropical and subtropical climates. Research during the last five decades has well established the negative effects of the mycotoxin on health of poultry. However, the last ten years of relevant data have accentuated the potential of low levels of aflatoxin B1 to deteriorate broiler performance. In this regard, any attempt to establish a dose-effect relationship between aflatoxin B1 level and broiler performance is also complicated due to differences in types of broilers and length of exposure to the mycotoxin in different studies. Contrary to the prevalent notion regarding literature saturation with respect to aflatoxicosis of chicken, many areas of aflatoxicosis still need to be explored. Literature regarding effects of the mycotoxin on the gastrointestinal tract in this regard is particular scanty and non-conclusive. In addition to these issues, the metabolism of aflatoxin B1 and recently proposed hypotheses regarding biphasic effects of the mycotoxin in broilers are briefly discussed.
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                Author and article information

                Journal
                Biomedical Letters
                Biomed. Lett.
                The Science Publishers
                2410-955X
                January 1 2022
                March 30 2022
                : 8
                : 1
                : 70-81
                Article
                10.47262/BL/8.1.20210901
                dfb79d1a-82ac-4474-ab69-12773e6fffcd
                © 2022
                History

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