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      Large-Scale Neuromorphic Spiking Array Processors: A Quest to Mimic the Brain

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          Abstract

          Neuromorphic engineering (NE) encompasses a diverse range of approaches to information processing that are inspired by neurobiological systems, and this feature distinguishes neuromorphic systems from conventional computing systems. The brain has evolved over billions of years to solve difficult engineering problems by using efficient, parallel, low-power computation. The goal of NE is to design systems capable of brain-like computation. Numerous large-scale neuromorphic projects have emerged recently. This interdisciplinary field was listed among the top 10 technology breakthroughs of 2014 by the MIT Technology Review and among the top 10 emerging technologies of 2015 by the World Economic Forum. NE has two-way goals: one, a scientific goal to understand the computational properties of biological neural systems by using models implemented in integrated circuits (ICs); second, an engineering goal to exploit the known properties of biological systems to design and implement efficient devices for engineering applications. Building hardware neural emulators can be extremely useful for simulating large-scale neural models to explain how intelligent behavior arises in the brain. The principal advantages of neuromorphic emulators are that they are highly energy efficient, parallel and distributed, and require a small silicon area. Thus, compared to conventional CPUs, these neuromorphic emulators are beneficial in many engineering applications such as for the porting of deep learning algorithms for various recognitions tasks. In this review article, we describe some of the most significant neuromorphic spiking emulators, compare the different architectures and approaches used by them, illustrate their advantages and drawbacks, and highlight the capabilities that each can deliver to neural modelers. This article focuses on the discussion of large-scale emulators and is a continuation of a previous review of various neural and synapse circuits (Indiveri et al., 2011). We also explore applications where these emulators have been used and discuss some of their promising future applications.

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          Most cited references120

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          Nanoscale memristor device as synapse in neuromorphic systems.

          A memristor is a two-terminal electronic device whose conductance can be precisely modulated by charge or flux through it. Here we experimentally demonstrate a nanoscale silicon-based memristor device and show that a hybrid system composed of complementary metal-oxide semiconductor neurons and memristor synapses can support important synaptic functions such as spike timing dependent plasticity. Using memristors as synapses in neuromorphic circuits can potentially offer both high connectivity and high density required for efficient computing.
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            Synaptic modifications in cultured hippocampal neurons: dependence on spike timing, synaptic strength, and postsynaptic cell type.

            Q Bi, G Bi, M Poo (1998)
            In cultures of dissociated rat hippocampal neurons, persistent potentiation and depression of glutamatergic synapses were induced by correlated spiking of presynaptic and postsynaptic neurons. The relative timing between the presynaptic and postsynaptic spiking determined the direction and the extent of synaptic changes. Repetitive postsynaptic spiking within a time window of 20 msec after presynaptic activation resulted in long-term potentiation (LTP), whereas postsynaptic spiking within a window of 20 msec before the repetitive presynaptic activation led to long-term depression (LTD). Significant LTP occurred only at synapses with relatively low initial strength, whereas the extent of LTD did not show obvious dependence on the initial synaptic strength. Both LTP and LTD depended on the activation of NMDA receptors and were absent in cases in which the postsynaptic neurons were GABAergic in nature. Blockade of L-type calcium channels with nimodipine abolished the induction of LTD and reduced the extent of LTP. These results underscore the importance of precise spike timing, synaptic strength, and postsynaptic cell type in the activity-induced modification of central synapses and suggest that Hebb's rule may need to incorporate a quantitative consideration of spike timing that reflects the narrow and asymmetric window for the induction of synaptic modification.
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              Neuromorphic electronic systems

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                Author and article information

                Contributors
                Journal
                Front Neurosci
                Front Neurosci
                Front. Neurosci.
                Frontiers in Neuroscience
                Frontiers Media S.A.
                1662-4548
                1662-453X
                03 December 2018
                2018
                : 12
                : 891
                Affiliations
                [1] 1Department of Electronic Systems Engineering, Indian Institute of Science , Bangalore, India
                [2] 2Department of Electrical and Computer Engineering, Johns Hopkins University , Baltimore, MD, United States
                [3] 3Department of Bioengineering and Institute for Neural Computation, University of California, San Diego , La Jolla, CA, United States
                [4] 4Institute of Neuroinformatics, University of Zurich and ETH Zurich , Zurich, Switzerland
                [5] 5Kirchhoff Institute for Physics, University of Heidelberg , Heidelberg, Germany
                [6] 6The MARCS Institute, Western Sydney University , Kingswood, NSW, Australia
                [7] 7Cognitive Interaction Technology – Center of Excellence, Bielefeld University , Bielefeld, Germany
                [8] 8School of Electrical and Computer Engineering, Georgia Institute of Technology , Atlanta, GA, United States
                [9] 9School of Electrical, Computer and Engineering, Arizona State University , Tempe, AZ, United States
                Author notes

                Edited by: Tim Pearce, University of Leicester, United Kingdom

                Reviewed by: Mattia Rigotti, IBM Research, United States; Leslie Samuel Smith, University of Stirling, United Kingdom

                *Correspondence: Chetan Singh Thakur csthakur@ 123456iisc.ac.in

                This article was submitted to Neuromorphic Engineering, a section of the journal Frontiers in Neuroscience

                Article
                10.3389/fnins.2018.00891
                6287454
                30559644
                df733933-dd61-49e6-9791-eeb26169bc9e
                Copyright © 2018 Thakur, Molin, Cauwenberghs, Indiveri, Kumar, Qiao, Schemmel, Wang, Chicca, Olson Hasler, Seo, Yu, Cao, van Schaik and Etienne-Cummings.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 20 January 2018
                : 14 November 2018
                Page count
                Figures: 30, Tables: 5, Equations: 8, References: 142, Pages: 37, Words: 23764
                Categories
                Neuroscience
                Review

                Neurosciences
                neuromorphic engineering,large-scale systems,brain-inspired computing,analog sub-threshold,spiking neural emulator

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