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      Using wearable sensors to classify subject-specific running biomechanical gait patterns based on changes in environmental weather conditions

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          Abstract

          Running-related overuse injuries can result from a combination of various intrinsic ( e. g., gait biomechanics) and extrinsic ( e. g., running surface) risk factors. However, it is unknown how changes in environmental weather conditions affect running gait biomechanical patterns since these data cannot be collected in a laboratory setting. Therefore, the purpose of this study was to develop a classification model based on subject-specific changes in biomechanical running patterns across two different environmental weather conditions using data obtained from wearable sensors in real-world environments. Running gait data were recorded during winter and spring sessions, with recorded average air temperatures of -10° C and +6° C, respectively. Classification was performed based on measurements of pelvic drop, ground contact time, braking, vertical oscillation of pelvis, pelvic rotation, and cadence obtained from 66,370 strides (~11,000/runner) from a group of recreational runners. A non-linear and ensemble machine learning algorithm, random forest (RF), was used to classify and compute a heuristic for determining the importance of each variable in the prediction model. To validate the developed subject-specific model, two cross-validation methods (one-against-another and partitioning datasets) were used to obtain experimental mean classification accuracies of 87.18% and 95.42%, respectively, indicating an excellent discriminatory ability of the RF-based model. Additionally, the ranked order of variable importance differed across the individual runners. The results from the RF-based machine-learning algorithm demonstrates that processing gait biomechanical signals from a single wearable sensor can successfully detect changes to an individual’s running patterns based on data obtained in real-world environments.

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          Random forests for classification in ecology.

          Classification procedures are some of the most widely used statistical methods in ecology. Random forests (RF) is a new and powerful statistical classifier that is well established in other disciplines but is relatively unknown in ecology. Advantages of RF compared to other statistical classifiers include (1) very high classification accuracy; (2) a novel method of determining variable importance; (3) ability to model complex interactions among predictor variables; (4) flexibility to perform several types of statistical data analysis, including regression, classification, survival analysis, and unsupervised learning; and (5) an algorithm for imputing missing values. We compared the accuracies of RF and four other commonly used statistical classifiers using data on invasive plant species presence in Lava Beds National Monument, California, USA, rare lichen species presence in the Pacific Northwest, USA, and nest sites for cavity nesting birds in the Uinta Mountains, Utah, USA. We observed high classification accuracy in all applications as measured by cross-validation and, in the case of the lichen data, by independent test data, when comparing RF to other common classification methods. We also observed that the variables that RF identified as most important for classifying invasive plant species coincided with expectations based on the literature.
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            Evaluation of variable selection methods for random forests and omics data sets

            Abstract Machine learning methods and in particular random forests are promising approaches for prediction based on high dimensional omics data sets. They provide variable importance measures to rank predictors according to their predictive power. If building a prediction model is the main goal of a study, often a minimal set of variables with good prediction performance is selected. However, if the objective is the identification of involved variables to find active networks and pathways, approaches that aim to select all relevant variables should be preferred. We evaluated several variable selection procedures based on simulated data as well as publicly available experimental methylation and gene expression data. Our comparison included the Boruta algorithm, the Vita method, recurrent relative variable importance, a permutation approach and its parametric variant (Altmann) as well as recursive feature elimination (RFE).  In our simulation studies, Boruta was the most powerful approach, followed closely by the Vita method. Both approaches demonstrated similar stability in variable selection, while Vita was the most robust approach under a pure null model without any predictor variables related to the outcome. In the analysis of the different experimental data sets, Vita demonstrated slightly better stability in variable selection and was less computationally intensive than Boruta. In conclusion, we recommend the Boruta and Vita approaches for the analysis of high-dimensional data sets. Vita is considerably faster than Boruta and thus more suitable for large data sets, but only Boruta can also be applied in low-dimensional settings.
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              Impact of weather on marathon-running performance.

              Marathon running performance slows in warm weather conditions, but the quantitative impact of weather has not been established. To quantify the impact of weather on marathon performance for different populations of runners. Marathon results and weather data were obtained for the Boston, New York, Twin Cities, Grandma's, Richmond, Hartford, and Vancouver Marathons for 36, 29, 24, 23, 6, 12, and 10 yr, respectively. The race results were broken into quartiles based on the wet-bulb globe temperature (Q1 5.1-10 degrees C, Q2 10.1-15 degrees C, Q3 15.1-20 degrees C, and Q4 20.1-25 degrees C). Analysis of the top three male and female finishers as well as the 25th-, 50th-, 100th-, and 300th-place finishers were compared with the course record and then contrasted with weather. Marathon performances of top males were slower than the course record by 1.7 +/- 1.5, 2.5 +/- 2.1, 3.3 +/- 2.0, and 4.5 +/- 2.3% (mean +/- SD) for Q1-Q4, respectively. Differences between Q4 and Q1, Q2, and between Q3, and Q1 were statistically different (P < 0.05). The top women followed a similar trend (Q1 3.2 +/- 4.9, Q2 3.2 +/- 2.9, Q3 3.8 +/- 3.2, and Q4 5.4 +/- 4.1% (mean +/- SD)), but the differences among quartiles were not statistically significant. The 25th-, 50th-, 100th-, and 300th-place finishers slowed more than faster runners as WBGT increased. For all runners, equivalence testing around a 1% indifference threshold suggests potentially important changes among quartiles independently of statistical significance. There is a progressive slowing of marathon performance as the WBGT increases from 5 to 25 degrees C. This seems true for men and women of wide ranging abilities, but performance is more negatively affected for slower populations of runners.
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                Author and article information

                Contributors
                Role: Data curationRole: MethodologyRole: Writing – original draftRole: Writing – review & editing
                Role: ConceptualizationRole: Writing – original draft
                Role: Formal analysisRole: ValidationRole: Writing – review & editing
                Role: InvestigationRole: SoftwareRole: Visualization
                Role: ResourcesRole: Software
                Role: Formal analysisRole: Writing – review & editing
                Role: ConceptualizationRole: Funding acquisitionRole: ResourcesRole: SupervisionRole: Writing – review & editing
                Role: Editor
                Journal
                PLoS One
                PLoS ONE
                plos
                plosone
                PLoS ONE
                Public Library of Science (San Francisco, CA USA )
                1932-6203
                18 September 2018
                2018
                : 13
                : 9
                : e0203839
                Affiliations
                [1 ] Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada
                [2 ] Running Injury Clinic, University of Calgary, Calgary, Alberta, Canada
                [3 ] Faculty of Nursing, University of Calgary, Calgary, Alberta, Canada
                University of Illinois at Urbana-Champaign, UNITED STATES
                Author notes

                Competing Interests: The authors have declared that no competing interests exist.

                Author information
                http://orcid.org/0000-0003-0497-7356
                http://orcid.org/0000-0002-4486-2062
                http://orcid.org/0000-0002-9056-0428
                Article
                PONE-D-18-13887
                10.1371/journal.pone.0203839
                6143236
                30226903
                dbede25f-ed0b-44a0-816a-bdb7a6baa550
                © 2018 Ahamed et al

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 8 May 2018
                : 28 August 2018
                Page count
                Figures: 4, Tables: 4, Pages: 15
                Funding
                Funded by: Natural Sciences and Engineering Research Council of Canada (CA)
                Award ID: NSERC: Discovery Grant 1028495 and Accelerator Award 1030390
                Award Recipient :
                Funded by: University of Calgary Eyes High Postdoctoral Research award
                Award Recipient :
                Funded by: Strategic Research Grant from the Vice-President (Research) at the University of Calgary
                Award Recipient :
                This study was partially funded by the Natural Sciences and Engineering Research Council of Canada (NSERC: Discovery Grant 1028495, Accelerator Award 1030390, and Idea-2 Innovation Awared I2IPJ 493875-16), a University of Calgary Eyes High Postdoctoral Research award, and a Strategic Research Grant from the Vice-President (Research) at the University of Calgary. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
                Categories
                Research Article
                Earth Sciences
                Seasons
                Winter
                Biology and Life Sciences
                Physiology
                Biological Locomotion
                Gait Analysis
                Medicine and Health Sciences
                Physiology
                Biological Locomotion
                Gait Analysis
                Earth Sciences
                Seasons
                Spring (Season)
                Biology and Life Sciences
                Biomechanics
                Biology and Life Sciences
                Anatomy
                Musculoskeletal System
                Pelvis
                Medicine and Health Sciences
                Anatomy
                Musculoskeletal System
                Pelvis
                Biology and Life Sciences
                Physiology
                Biological Locomotion
                Running
                Medicine and Health Sciences
                Physiology
                Biological Locomotion
                Running
                Medicine and Health Sciences
                Critical Care and Emergency Medicine
                Trauma Medicine
                Traumatic Injury
                Musculoskeletal Injury
                Earth Sciences
                Geography
                Cartography
                Longitude
                Custom metadata
                Relevant data are included with the submission, any additional data (e.g., remaining 5 runners data) will be available upon request from the Running Injury Clinic and University of Calgary Institutional Data Access / Ethics Committee (CHREB) by contacting Dr. Stacey A. Page, chair of CHREB at omb@ 123456ucalgary.ca .

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