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      A Short Review on Polymer, Metal and Ceramic Based Implant Materials

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      IOP Conference Series: Materials Science and Engineering
      IOP Publishing

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          Abstract

          The present work focuses on the evaluation of polymer, metal and ceramic based biomaterials with particular emphasis on success rate of these materials till date along with the merits and demerits of these material system. Currently, the search for the materials with improved performance is on rise for biomedical (mainly total hip replacement, THR) applications owing to increase in the number of orthopedic patients worldwide. The clinicians utilized polymer and metal-based implants in ancient times to heal and treat the bone imperfections as well as fractures. The next generation materials required an update on properties, cell material interactions, repair and regeneration, that can only be acquired from recent knowledge related to materials. The commonly employed polymers (natural based polymers, proteins or polysaccharides; and synthetic polymers, poly (lactic acid), poly (glycolic acid), poly (ε-caprolactone), poly(3-hydroxybutyrate) (PHB)) and metals (SS, Mg-alloy, Ti-alloys, Co-alloy, silver, and nickel-titanium alloys) failed to fulfill the long-term durability and lacked in generating adequate bonding with the bones. It is intended that the facts and details abridged in this review article ought to be a beneficial tool in the development of progressively eminent implant materials like ceramic based materials against premature failure, cyclic stress generation, wear, corrosion fatigue, implant loosening and ultimate fracture.

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          In vivo corrosion of four magnesium alloys and the associated bone response.

          Degrading metal alloys are a new class of implant materials suitable for bone surgery. The aim of this study was to investigate the degradation mechanism at the bone-implant interface of different degrading magnesium alloys in bone and to determine their effect on the surrounding bone. Sample rods of four different magnesium alloys and a degradable polymer as a control were implanted intramedullary into the femora of guinea pigs. After 6 and 18 weeks, uncalcified sections were generated for histomorphologic analysis. The bone-implant interface was characterized in uncalcified sections by scanning electron microscopy (SEM), element mapping and X-ray diffraction. Results showed that metallic implants made of magnesium alloys degrade in vivo depending on the composition of the alloying elements. While the corrosion layer of all magnesium alloys accumulated with biological calcium phosphates, the corrosion layer was in direct contact with the surrounding bone. The results further showed high mineral apposition rates and an increased bone mass around the magnesium rods, while no bone was induced in the surrounding soft tissue. From the results of this study, there is a strong rationale that in this research model, high magnesium ion concentration could lead to bone cell activation.
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            Metallic implant biomaterials

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              Nanoscale hydroxyapatite particles for bone tissue engineering.

              Hydroxyapatite (HAp) exhibits excellent biocompatibility with soft tissues such as skin, muscle and gums, making it an ideal candidate for orthopedic and dental implants or components of implants. Synthetic HAp has been widely used in repair of hard tissues, and common uses include bone repair, bone augmentation, as well as coating of implants or acting as fillers in bone or teeth. However, the low mechanical strength of normal HAp ceramics generally restricts its use to low load-bearing applications. Recent advancements in nanoscience and nanotechnology have reignited investigation of nanoscale HAp formation in order to clearly define the small-scale properties of HAp. It has been suggested that nano-HAp may be an ideal biomaterial due to its good biocompatibility and bone integration ability. HAp biomedical material development has benefited significantly from advancements in nanotechnology. This feature article looks afresh at nano-HAp particles, highlighting the importance of size, crystal morphology control, and composites with other inorganic particles for biomedical material development. Copyright © 2011 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
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                Author and article information

                Journal
                IOP Conference Series: Materials Science and Engineering
                IOP Conf. Ser.: Mater. Sci. Eng.
                IOP Publishing
                1757-8981
                1757-899X
                January 01 2021
                January 01 2021
                : 1017
                : 1
                : 012038
                Article
                10.1088/1757-899X/1017/1/012038
                dbe7f995-e78d-4b49-8644-5793c783b0d5
                © 2021

                http://creativecommons.org/licenses/by/3.0/

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