Sentinel European Node Trial (SENT): 3-year results of sentinel node biopsy in oral cancer.

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Abstract

Optimum management of the N0 neck is unresolved in oral cancer. Sentinel node biopsy (SNB) can reliably detect microscopic lymph node metastasis. The object of this study was to establish whether the technique was both reliable in staging the N0 neck and a safe oncological procedure in patients with early-stage oral squamous cell carcinoma.

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Journal

Journal ID (iso-abbrev): Eur. J. Cancer

Title: European journal of cancer (Oxford, England : 1990)

ISSN (Electronic): 1879-0852

ISSN (Print): 0959-8049

Publication date (Electronic): Dec 2015

Volume: 51

Issue: 18

Affiliations

[1 ] Department of Head and Neck Surgery, Guys and St Thomas NHS Trust, London, UK.

[2 ] Department of Otorhinolaryngology, Head and Neck Surgery Kantonsspital St Gallen, Switzerland.

[3 ] Department of Head and Neck Surgery, University of Basel, Switzerland.

[4 ] Department of Otolaryngology University Hospital Zurich, Switzerland.

[5 ] Department of Plastic and Reconstructive Surgery, Odense University Hospital, Denmark.

[6 ] Department of Pathology, Odense University Hospital, Denmark.

[7 ] Department of Otolaryngology Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen, Denmark.

[8 ] Head and Neck/Oral Pathology, King's College London, Guys and St Thomas NHS Trust, London, UK.

[9 ] Department of Nuclear Medicine, Guys and St Thomas NHS Trust, London, UK.

[10 ] Department of Otolaryngology Head and Neck Surgery, VU University Medical Center, Amsterdam, The Netherlands.

[11 ] Department of Pathology, VU University Medical Centre and Academic Centre of Dentistry Amsterdam, The Netherlands.

[12 ] Department of Maxillofacial Surgery, Hospital Universitario Central de Asturias, Oviedo, Spain.

[13 ] Department of Pathology, Hospital Universitario Central de Asturias, Oviedo, Spain.

[14 ] Department of Maxillofacial Surgery, BioCruces, Hospital Universitario De Cruces, Universidad del Pais Vasco (UPV/EHU), Bilbao, Spain.

[15 ] Department of Head and Neck Surgery, Instituto Portugues de Oncologia do Porto, Portugal.

[16 ] Department of Otorhinolaryngology, San Carlo Hospital Rome, Italy.

[17 ] Department of Histopathology, San Carlo Hospital Rome, Italy.

[18 ] Department of Nuclear Medicine, Cristo Re Hospital, Rome, Italy.

[19 ] Department of Head and Neck Surgery, CHU Dinant Godinne, Université Catholique de Louvain, Belgium.

[20 ] Department of Otolaryngology, Ospedale S. Chiara, Trento, Italy.

[21 ] Department of Nuclear Medicine, Ospedale S. Chiara, Trento, Italy.

[22 ] Department of Surgical Pathology, Ospedale S. Chiara, Trento, Italy.

[23 ] Department of Maxillofacial Surgery CHU de Charleroi Belgium, Belgium.

[24 ] Department of Maxillofacial Surgery, Azienda Ospedaliera, Universitaria of Parma, Italy.

[25 ] Department of Pathology Azienda Ospedaliera Universitaria of Parma, Italy.

[26 ] Department of Head and Neck Surgery Centre Alexis Vautrin, Vandoeuvre Les Nancy, France.

[27 ] Department of Pathology Centre Alexis Vautrin, Vandoeuvre Les Nancy, France.

[28 ] Department of Informatics, Kings' College London, UK.

[29 ] Department of Cellular Pathology, Newcastle University Hospital, UK.

[30 ] Department of Head and Neck Surgery, Guys and St Thomas NHS Trust, London, UK. Electronic address: mark.mcgurk@kcl.ac.uk.

Article

Publisher Item ID: S0959-8049(15)00822-9

DOI: 10.1016/j.ejca.2015.08.023

PubMed ID: 26597442

SO-VID: db2d1794-5928-46fc-b6c2-b9d597d9d0ce

History

Keywords: Lymphoscintigraphy,Metastasis,Micrometastasis,Oral Cancer,Recurrence,Sentinel lymph node biopsy

Data availability:

Keywords: Lymphoscintigraphy, Metastasis, Micrometastasis, Oral Cancer, Recurrence, Sentinel lymph node biopsy

Sentinel European Node Trial (SENT): 3-year results of sentinel node biopsy in oral cancer.

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