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      Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies.

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          Abstract

          The decision of whether to treat incidental intracranial saccular aneurysms is complicated by limitations in current knowledge of their natural history. We combined individual patient data from prospective cohort studies to determine predictors of aneurysm rupture and to construct a risk prediction chart to estimate 5-year aneurysm rupture risk by risk factor status.

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          Author and article information

          Journal
          Lancet Neurol
          The Lancet. Neurology
          Elsevier BV
          1474-4465
          1474-4422
          Jan 2014
          : 13
          : 1
          Affiliations
          [1 ] Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands. Electronic address: j.p.greving@umcutrecht.nl.
          [2 ] Department of Neurology, Leiden University Medical Center, Leiden, Netherlands.
          [3 ] Department of Neurology, Mayo Clinic, Rochester, MN, USA.
          [4 ] UCAS Japan Coordinating Office, University of Tokyo, Tokyo, Japan; Department of Neurological Surgery, Nippon Medical School, Tokyo, Japan.
          [5 ] Department of Clinical Neurosciences, University of Helsinki, Helsinki, Finland.
          [6 ] Department of Neurosurgery, National Nagasaki Medical Center, Nagasaki, Japan.
          [7 ] Division of Endovascular Neurosurgery, Tokyo Jikei University School of Medicine, Tokyo, Japan.
          [8 ] Department of Epidemiology, University of Iowa, Iowa City, IA, USA.
          [9 ] Department of Health Informatics, Kyoto University School of Public Health, Kyoto, Japan.
          [10 ] Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands.
          [11 ] Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands; Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands.
          Article
          S1474-4422(13)70263-1
          10.1016/S1474-4422(13)70263-1
          24290159
          db265e38-e453-45db-9763-1aae60d4d22a
          Copyright © 2014 Elsevier Ltd. All rights reserved.
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