Peter Petschner: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: MethodologyRole:
Writing – original draftRole: Writing – review & editing
Daniel Baksa:
ORCID: https://orcid.org/0000-0002-7826-9179
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: MethodologyRole:
Writing – original draftRole: Writing – review & editing
Gabor Hullam: Role: Data curationRole: Formal analysisRole: MethodologyRole: Writing – original
draftRole: Writing – review & editing
Dora Torok: Role: Data curationRole: Formal analysisRole: MethodologyRole: VisualizationRole:
Writing – original draftRole: Writing – review & editing
Andras Millinghoffer: Role: Data curationRole: Formal analysisRole: Writing – original draftRole: Writing
– review & editing
J. F. William Deakin: Role: Funding acquisitionRole: InvestigationRole: Writing – original draftRole: Writing
– review & editing
Gyorgy Bagdy: Role: Funding acquisitionRole: InvestigationRole: Writing – original draftRole: Writing
– review & editing
Gabriella Juhasz:
ORCID: https://orcid.org/0000-0002-5975-4267
Role: ConceptualizationRole: Funding acquisitionRole: InvestigationRole: SupervisionRole:
Writing – original draftRole: Writing – review & editing
Badri Padhukasahasram: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS One
Journal ID (publisher-id): plos
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
31
December
2021
Publication date Collection: 2021
Volume: 16
Issue: 12
Electronic Location Identifier: e0261477
Affiliations
[1
]
Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho,
Uji, Kyoto, Japan
[2
]
Department of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University, Budapest,
Hungary
[3
]
MTA-SE Neuropsychopharmacology and Neurochemistry Research Group, Hungarian Academy
of Sciences, Semmelweis University, Budapest, Hungary
[4
]
SE-NAP2 Genetic Brain Imaging Migraine Research Group, Hungarian Brain Research Program,
Semmelweis University, Budapest, Hungary
[5
]
Department of Measurement and Information Systems, Budapest University of Technology
and Economics, Budapest, Hungary
[6
]
NAP-2-SE New Antidepressant Target Research Group, Semmelweis University, Budapest,
Hungary
[7
]
Neuroscience and Psychiatry Unit, Division of Neuroscience and Experimental Psychology,
The University of Manchester and Manchester Academic Health Sciences Centre, Manchester,
United Kingdom
Illumina Inc, UNITED STATES
Author notes
Competing Interests: J. F. William Deakin has share options in P1vital and Gyorgy Bagdy is a member of
the Board of directors at Gedeon Richter. The other authors declare no competing interests
exist.
Author information
Article
Publisher ID:
PONE-D-21-17017
DOI: 10.1371/journal.pone.0261477
PMC ID: 8719675
PubMed ID: 34972135
SO-VID: da55be75-6ae6-4db8-bb7c-fb87250a0ad8
Copyright © © 2021 Petschner et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by:
Ministry of Human Capacities, Hungary
Award ID: BME FIKP-BIO
Award Recipient
:
Gabor Hullam
Funded by:
Hungarian Brain Research Program, National Development Agency
Award ID: 2017-1.2.1-NKP-2017-00002; KTIA_13_NAPA-II/14; KTIA_NAP_13-1-2013-0001
Award Recipient
:
Gyorgy Bagdy
Funded by:
Hungarian Academy of Sciences, Semmelweis University and the Hungarian Brain Research
Program
Award ID: KTIA_NAP_13-2-2015-0001
Award Recipient
:
ORCID: https://orcid.org/0000-0002-5975-4267
Gabriella Juhasz
Funded by:
Sixth Framework Program of the European Union, NewMood
Award ID: LSHM-CT-2004-503474
Award Recipient
:
Gyorgy Bagdy
Funded by:
National Institute for Health Research Manchester Biomedical Research Centre
Award Recipient
:
J. F. William Deakin
Funded by:
Hungarian Academy of Sciences (MTA-SE Neuropsychopharmacology and Neurochemistry Research
Group)
Award Recipient
:
Gabor Hullam
Funded by:
National Research, Development and Innovation Office, Hungary under the frame of ERA
PerMed
Award ID: 2019-2.1.7-ERA-NET-2020-00005; ERAPERMED2019-108
Award Recipient
:
ORCID: https://orcid.org/0000-0002-5975-4267
Gabriella Juhasz
Funded by:
New National Excellence Program of Ministry of Human Capacities
Award ID: UNKP-17-4-I-SE-8
Award Recipient
:
Peter Petschner
Funded by:
New National Excellence Program of Ministry of Human Capacities
Award ID: UNKP-19-4-BME-344
Award Recipient
:
Gabor Hullam
Funded by:
New National Excellence Program of the Ministry for Innovation and Technology from
the source of the National Research, Development and Innovation Fund
Award ID: ÚNKP-20-3-II-SE-51
Award Recipient
:
ORCID: https://orcid.org/0000-0002-7826-9179
Daniel Baksa
Funded by:
New National Excellence Program of the Ministry for Innovation and Technology from
the source of the National Research, Development and Innovation Fund
Award ID: ÚNKP-20-5-BME-92
Award Recipient
:
Gabor Hullam
Funded by:
Thematic Excellence Programme (Tématerületi Kiválósági Program) of the Ministry for
Innovation and Technology in Hungary, within the framework of the Neurology and Translational
Biotechnology thematic programmes of the Semmelweis University
Award ID: 2020-4.1.1.-TKP2020
Award Recipient
:
ORCID: https://orcid.org/0000-0002-5975-4267
Gabriella Juhasz
Funded by:
OTKA
Award ID: 119866
Award Recipient
:
Gabor Hullam
Funded by:
NRDI Fund based on the charter of bolster issued by the NRDI Office under the auspices
of the Ministry for Innovation and Technology
Award ID: BME NC TKP2020, BME IE-BIO TKP2020
Award Recipient
:
Gabor Hullam
Funded by:
Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences
Award Recipient
:
Gabor Hullam
Funded by:
Japan Society for the Promotion of Science (Postdoctoral Fellowships for Research
in Japan, standard program)
Award ID: P20809
Award Recipient
:
Peter Petschner
Funded by:
New National Excellence Program of the Ministry for Innovation and Technology from
the source of the National Research, Development and Innovation Fund
Award ID: ÚNKP-21-5-BME-362
Award Recipient
:
Gabor Hullam
Funded by:
New National Excellence Program of the Ministry for Innovation and Technology from
the source of the National Research, Development and Innovation Fund
Award ID: ÚNKP-21-4-I-SE-15
Award Recipient
:
ORCID: https://orcid.org/0000-0002-7826-9179
Daniel Baksa
Our study was part of NewMood (New Molecules in Mood Disorders, 2004-2009) research
program funded by the European Union and was supported by the Hungarian Brain Research
Program (KTIA_13_NAP-A-II/14, 2017-1.2.1-NKP-2017-00002); by the National Development
Agency (KTIA_NAP_13-1-2013-0001); by the Sixth Framework Program of the European Union,
NewMood (Grant No. LSHM-CT-2004-503474); by the Hungarian Academy of Sciences, Semmelweis
University and the Hungarian Brain Research Program (MTA-SE-NAP B Genetic Brain Imaging
Migraine Research Group, Grant KTIA_NAP_13-2-2015-0001); by the National Institute
for Health Research Manchester Biomedical Research Centre; by the Hungarian Academy
of Sciences (MTA-SE Neuropsychopharmacology and Neurochemistry Research Group); by
the National Research, Development and Innovation Office, Hungary (2019-2.1.7-ERA-NET-2020-00005),
under the frame of ERA PerMed (ERAPERMED2019-108); by the New National Excellence
Program of Ministry of Human Capacities (UNKP-17-4-I-SE-8, UNKP-19-4-BME-344); by
the New National Excellence Program of the Ministry for Innovation and Technology
from the source of the National Research, Development and Innovation Fund (ÚNKP-20-3-II-SE-51,
ÚNKP-20-5-BME-92, ÚNKP-21-5-BME-362, ÚNKP-21-4-I-SE-15); by the BME-Biotechnology
FIKP grant of EMMI (BME FIKP-BIO); by the Thematic Excellence Programme (Tématerületi
Kiválósági Program, 2020-4.1.1.-TKP2020) of the Ministry for Innovation and Technology
in Hungary, within the framework of the Neurology and Translational Biotechnology
thematic programmes of the Semmelweis University; by OTKA 119866; and by the NRDI
Fund (BME NC TKP2020, BME IE-BIO TKP2020, Artificial Intelligence National Laboratory
Programme) based on the charter of bolster issued by the NRDI Office under the auspices
of the Ministry for Innovation and Technology. GH is a recipient of the Janos Bolyai
Research Scholarship of the Hungarian Academy of Sciences. PP is an international
research fellow of Japan Society for the Promotion of Science (Postdoctoral Fellowships
for Research in Japan, standard program, P20809). The funders had no role in study
design, data collection and analysis, decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Clinical Medicine
Subject:
Signs and Symptoms
Subject:
Headaches
Subject:
Migraine
Subject:
Medicine and Health Sciences
Subject:
Mental Health and Psychiatry
Subject:
Mood Disorders
Subject:
Depression
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Single Nucleotide Polymorphisms
Subject:
Medicine and Health Sciences
Subject:
Epidemiology
Subject:
Medical Risk Factors
Subject:
Computer and Information Sciences
Subject:
Neural Networks
Subject:
Biology and Life Sciences
Subject:
Neuroscience
Subject:
Neural Networks
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Biology and Life Sciences
Subject:
Computational Biology
Subject:
Genome Analysis
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Genomics
Subject:
Genome Analysis
Subject:
Biology and Life Sciences
Subject:
Computational Biology
Subject:
Genome Analysis
Subject:
Genome-Wide Association Studies
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Genomics
Subject:
Genome Analysis
Subject:
Genome-Wide Association Studies
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Human Genetics
Subject:
Genome-Wide Association Studies
