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      PD-L1 (Programmed Death Ligand 1) Protects Against Experimental Intracerebral Hemorrhage-Induced Brain Injury.

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          Abstract

          Intracerebral hemorrhage (ICH) is a neurologically destructive stroke, for which no valid treatment is available. This preclinical study examined the therapeutic effect of PD-L1 (programmed death ligand 1), a B7 family member and a ligand for both PD-1 (programmed death 1) and B7-1 (CD80), in a murine ICH model.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Stroke
          Title: Stroke
          Publisher: Ovid Technologies (Wolters Kluwer Health)
          ISSN (Electronic): 1524-4628
          ISSN (Print): 0039-2499
          Publication date (Electronic): August 2017
          Volume: 48
          Issue: 8
          Affiliations
          [1 ] From the Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, China.
          [2 ] From the Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, China. hjw@tmu.edu.cn.
          Article
          Publisher Item ID: STROKEAHA.117.016705
          DOI: 10.1161/STROKEAHA.117.016705
          PubMed ID: 28706113
          SO-VID: d9b100a2-fd6d-4d62-9fd5-5b324659cbc3
          History

          Keywords: stroke,inflammation,PD-L1,cerebral hemorrhage,hematoma
          Data availability:
          Keywords: stroke, inflammation, PD-L1, cerebral hemorrhage, hematoma

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