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Inducible metronidazole resistance and nim genes in clinical Bacteroides fragilis group isolates.

Author(s): Charlotta Edlund, Hong-Fang Ji, Sonja Löfmark, Maria Hedberg

Publication date: 2005-02-28

Journal: Antimicrobial Agents and Chemotherapy

Keywords: Bacteroides fragilis, drug effects, genetics, Drug Resistance, Bacterial, Genes, Bacterial, Humans, Metronidazole, pharmacology, Microbial Sensitivity Tests

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Abstract

Nitroimidazole resistance (nim) genes were detected in 2% of 1,502 clinical Bacteroides fragilis group strains isolated from 19 European countries, and a novel nim gene was identified. High metronidazole resistance could be induced in nim-positive strains, which emphasizes the importance of acknowledging metronidazole resistance in the clinical setting.

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PubMed ID:: 15728943

PMC ID:: 549250

DOI:: 10.1128/AAC.49.3.1253-1256.2005

ScienceOpen disciplines: Chemistry

Keywords: Bacteroides fragilis,drug effects,genetics,Drug Resistance, Bacterial,Genes, Bacterial,Humans,Metronidazole,pharmacology,Microbial Sensitivity Tests

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ScienceOpen disciplines: Chemistry

Keywords: Bacteroides fragilis, drug effects, genetics, Drug Resistance, Bacterial, Genes, Bacterial, Humans, Metronidazole, pharmacology, Microbial Sensitivity Tests

Inducible metronidazole resistance and nim genes in clinical Bacteroides fragilis group isolates.

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