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What We Talk About When We Talk About Fat
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Abstract
There has been an upsurge of interest in the adipocyte coincident with the onset of
the obesity epidemic and the realization that adipose tissue plays a major role in
the regulation of metabolic function. The past few years, in particular, have seen
significant changes in the way that we classify adipocytes and how we view adipose
development and differentiation. We have new perspective on the roles played by adipocytes
in a variety of homeostatic processes and on the mechanisms used by adipocytes to
communicate with other tissues. Finally, there has been significant progress in understanding
how these relationships are altered during metabolic disease and how they might be
manipulated to restore metabolic health.
Copyright © 2014 Elsevier Inc. All rights reserved.