Allergen immunotherapy for IgE-mediated food allergy: a systematic review and meta-analysis.

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Abstract

The European Academy of Allergy and Clinical Immunology (EAACI) is developing Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated Food Allergy. To inform the development of clinical recommendations, we sought to critically assess evidence on the effectiveness, safety and cost-effectiveness of AIT in the management of food allergy.

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Journal

Journal ID (iso-abbrev): Allergy

Title: Allergy

Publisher: Wiley-Blackwell

ISSN (Electronic): 1398-9995

ISSN (Print): 0105-4538

Publication date (Electronic): Jan 06 2017

Affiliations

[1 ] Cardiff University, School of Medicine, Division of Population Medicine Neuadd Meirionnydd, Heath Park, Cardiff, UK.

[2 ] Evidence-Based Health Care Ltd, Edinburgh, UK.

[3 ] Department of Pediatrics, Allergy Unit, University of Messina, Italy.

[4 ] Molecular Allergology and Immunomodulation-Department of Pediatric Pneumology and Immunology, Charité Medical University, Augustenburger Platz 1, Berlin, Germany.

[5 ] Allergy Department, Hospital Clínico San Carlos, IdISSC, Madrid, Spain.

[6 ] Food Allergy Referral Centre Veneto Region Department of Women and Child Health Padua General University Hospital, Italy.

[7 ] The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport Isle of Wight/ NIHR Respiratory Biomedical Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

[8 ] Faculty of Medicine, University of Southampton, Southampton, UK.

[9 ] Swiss Institute for Allergy and Asthma Research.

[10 ] Paediatric Allergy and Clinical Immunology Section, Hospital Sant Joan de Déu, Universitat de Barcelona, Barcelona, Spain.

[11 ] Charité Universitätsmedizin, Pediatric Pneumology and Immunology, Berlin, Germany.

[12 ] Icahn School of Medicine at Mount Sinai, New York, United States.

[13 ] Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Denmark.

[14 ] University of North Carolina at Chapel Hill, School of Medicine, Department of Pediatrics, Chapel Hill, NC, USA.

[15 ] Department of Paediatric Allergy, MRC & Asthma Centre in Allergic Mechanisms of Asthma, Division of Asthma, Allergy and Lung Biology, King's College London and St Thomas NHS Foundation trust, London, United Kingdom.

[16 ] Department of Allergy, Clinical Research Center for Allergy & Rheumatology, Sagamihara National Hospital, Sagamihara, Kanagawa, Japan.

[17 ] University Hospitals of Geneva and Medical School of the University of Geneva, Switzerland.

[18 ] Department of Immunology and Department of Dermatology & Allergology, University Medical Center Utrecht, the Netherlands.

[19 ] Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland.

[20 ] Department of Pediatrics, Division of Immunology, Allergy and Rheumatology, Stanford University, Stanford, California, USA.

[21 ] Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.

[22 ] University of Athens, 2nd Pediatric Clinic, Allergy.

[23 ] Allergy Clinic, Copenhagen University Hospital, Gentofte, Denmark.

[24 ] Pediatric Allergist at Koç University Hospital.

[25 ] World Allergy Organization (WAO).

[26 ] Department of Paediatric Allergy, Division of Asthma Allergy and Lung Biology, King's College London/Guy's and St Thomas' Hospital NHS Foundation Trust, London, UK.

[27 ] Department of Otorhinolaryngology, Academic Medical Center, Amsterdam, The Netherlands.

[28 ] Nederlands Anafylaxis Netwerk - European Anaphylaxis Taskforce, Dordrecht, The Netherlands.

[29 ] Allergy and Respiratory Research Group, Centre of Medical Informatics, Usher Institue of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, UK.

Article

DOI: 10.1111/all.13124

PubMed ID: 28058751

SO-VID: d81459ab-76e4-4b9f-bc8f-9048d265abbe

History

Keywords: Allergen,allergen immunotherapy,desensitization,food allergy,safety,sensitization,sustained unresponsiveness

Data availability:

Keywords: Allergen, allergen immunotherapy, desensitization, food allergy, safety, sensitization, sustained unresponsiveness

Allergen immunotherapy for IgE-mediated food allergy: a systematic review and meta-analysis.

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