IDDM2/insulin VNTR modifies risk conferred by IDDM1/HLA for development of Type 1 diabetes and associated autoimmunity.

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Abstract

Type 1 diabetes (T1D) is an autoimmune disease with multiple susceptibility genes. The aim of this study was to determine whether combining IDDM1/HLA and IDDM2/ insulin( INS) 5' variable number of tandem repeat locus (VNTR) genotypes improves T1D risk assessment.

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Journal

Journal ID (iso-abbrev): Diabetologia

Title: Diabetologia

Publisher: Springer Science and Business Media LLC

ISSN: 0012-186X

ISSN (Print): 0012-186X

Publication date (Electronic): May 2003

Volume: 46

Issue: 5

Affiliations

[1 ] Diabetes Research Institute, Munich-Schwabing Hospital, Kölner Platz 1, 80804 Munich, Germany.

Article

DOI: 10.1007/s00125-003-1082-z

PubMed ID: 12750767

SO-VID: d69a7f00-2b44-4e08-9e68-d0fe6baf3e02

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