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Impaired wound healing in a migraine patient as a possible side effect of calcitonin gene-related peptide receptor antibody treatment: A case report.
Sebastian Wurthmann
1 ,
Steffen Nägel
1
,
2 ,
Eva Hadaschik
3 ,
Swantje Schlott
3 ,
Armin Scheffler
1 ,
Christoph Kleinschnitz
1 ,
Dagny Holle
1
October 2020
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Abstract
Wound healing disturbances as possible side effects of calcitonin gene-related peptide (CGRP) antibody treatment have been discussed previously but not yet described in humans. Basic research suggests that calcitonin gene-related peptide plays an important role in keratinocyte migration, vascularization and immune response and lack of calcitonin gene-related peptide may lead to impaired wound healing.