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      Detection, prevention and treatment of COVID‐19 and opportunities for nanobiotechnology

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          Abstract

          Since the outbreak of COVID‐19, the number of confirmed cases and deaths has increased globally at a dramatic speed. In view of the serious health threat to humans, this review discusses the state‐of‐the‐art studies about fighting this disease. It summarizes the current strategies and recent advances in detecting, preventing, and treating COVID‐19 and interprets the underlying mechanisms in detail. Detection of COVID‐19 can be successfully achieved by multiple techniques such as polymerase chain reaction, computed tomography imaging, and nano‐biosensing. Inactivated virus vaccine, nucleic acid vaccine, and different nanoparticles have been employed to effectively prevent COVID‐19. A variety of agents such as antiviral agents, neutralizing antibodies, and nanotherapeutics have been developed to treat COVID‐19 with exciting efficacy. Although nanobiotechnology has shown great potential in the diagnosis, prevention, and treatment of COVID‐19, efforts should be made to explore new biocompatible nano‐biomaterials to advance this field to clinical applications. Hence, nanobiotechnology paves a new way to detect, prevent, and treat COVID‐19 effectively.

          Abstract

          Since the outbreak of COVD‐19, the number of confirmed cases and deaths has increased globally at a dramatic speed. In view of the serious health threat to humans, this review discusses the state‐of‐the‐art studies about fighting this disease. It summarizes the current strategies and recent advances in detecting, preventing, and treating COVID‐19 and interprets the underlying mechanisms in detail.

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          Consensus document on the epidemiology of severe acute respiratory syndrome (SARS)

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            Author and article information

            Contributors
            yangm@zju.edu.cn
            maophage@gmail.com , cbmao@ou.edu
            Journal
            View (Beijing)
            View (Beijing)
            10.1002/(ISSN)2688-268X
            VIW2
            View (Beijing, China)
            John Wiley and Sons Inc. (Hoboken )
            2688-3988
            2688-268X
            15 March 2022
            15 March 2022
            : 20200181
            Affiliations
            [ 1 ] School of Materials Science and Engineering Zhejiang University Hangzhou Zhejiang China
            [ 2 ] College of Animal Science Institute of Applied Bioresource Research Zhejiang University Hangzhou Zhejiang China
            [ 3 ] Department of Chemistry and Biochemistry University of Oklahoma Norman Oklahoma USA
            Author notes
            [*] [* ] Correspondence

            Mingying Yang, Institute of Applied Bioresource Research, College of Animal Science, Zhejiang University, Hangzhou, Zhejiang, China

            Email: yangm@ 123456zju.edu.cn

            Chuanbin Mao, Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma, USA

            Email: maophage@ 123456gmail.com or cbmao@ 123456ou.edu

            Author information
            https://orcid.org/0000-0002-8142-3659
            Article
            VIW2206
            10.1002/VIW.20200181
            9111118
            d67a9e88-48ca-4b99-9865-ed50345f1053
            © 2022 The Authors. VIEW published by Shanghai Fuji Technology Consulting Co., Ltd, authorized by Professional Community of Experimental Medicine, National Association of Health Industry and Enterprise Management (PCEM) and John Wiley & Sons Australia, Ltd.

            This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

            History
            : 12 January 2022
            : 24 October 2021
            : 08 February 2022
            Page count
            Figures: 17, Tables: 0, Pages: 19, Words: 11452
            Funding
            Funded by: National Natural Science Foundation of China , doi 10.13039/501100001809;
            Award ID: 51673168
            Award ID: 81871499
            Award ID: 31800807
            Funded by: Zhejiang Provincial Natural Science Foundation of China
            Award ID: LZ17C170002
            Award ID: LZ16E030001
            Funded by: Fundamental Research Funds for the Central Universities , doi 10.13039/501100012226;
            Award ID: 2018XZZX001‐11
            Funded by: State of Sericulture Industry Technology System
            Award ID: CARS‐18‐ZJ0501
            Funded by: Zhejiang Provincial Science and Technology Plans
            Award ID: 2016C02054‐19
            Funded by: Zhejiang Provincial Key Laboratory Construction Plans
            Award ID: 2020E10025
            Funded by: Zhejiang Province Public Welfare Technology Research Plans
            Award ID: LGF21H060008
            Categories
            Review
            Reviews
            Custom metadata
            2.0
            corrected-proof
            Converter:WILEY_ML3GV2_TO_JATSPMC version:6.1.6 mode:remove_FC converted:17.05.2022

            diagnosis,nanobiotechnology,nanotechnology,prevention,treatment,virus

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