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      Non-communicable diseases in low- and middle-income countries: context, determinants and health policy.

      Tropical Medicine & International Health
      Cardiovascular Diseases, epidemiology, prevention & control, Chronic Disease, mortality, Developing Countries, Diabetes Mellitus, Female, Health Policy, Health Transition, Humans, Life Style, Male, Mental Disorders, Neoplasms, Nutrition Policy, Obesity, complications, Quality Assurance, Health Care, standards, Risk Factors

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          Abstract

          The rise of non-communicable diseases and their impact in low- and middle-income countries has gained increased attention in recent years. However, the explanation for this rise is mostly an extrapolation from the history of high-income countries whose experience differed from the development processes affecting today's low- and middle-income countries. This review appraises these differences in context to gain a better understanding of the epidemic of non-communicable diseases in low- and middle-income countries. Theories of developmental and degenerative determinants of non-communicable diseases are discussed to provide strong evidence for a causally informed approach to prevention. Health policies for non-communicable diseases are considered in terms of interventions to reduce population risk and individual susceptibility and the research needs for low- and middle-income countries are discussed. Finally, the need for health system reform to strengthen primary care is highlighted as a major policy to reduce the toll of this rising epidemic.

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