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      Mortality following myocardial infarction among HIV-infected persons: the Center for AIDS Research Network Of Integrated Clinical Systems (CNICS).

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          Abstract

          Persons with human immunodeficiency virus (HIV) have higher risks for myocardial infarction (MI) than the general population. This is driven in part by higher type 2 MI (T2MI, due to coronary supply-demand mismatch) rates among persons with HIV (PWH). In the general population, T2MI has higher mortality than type 1 MI (T1MI, spontaneous and generally due to plaque rupture and thrombosis). PWH have a greater burden of comorbidities and may therefore have an even greater excess risk for complication and death in the setting of T2MI. However, mortality patterns after T1MI and T2MI in HIV are unknown.

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          Author and article information

          Journal
          BMC Med
          BMC medicine
          Springer Science and Business Media LLC
          1741-7015
          1741-7015
          July 31 2019
          : 17
          : 1
          Affiliations
          [1 ] Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, 680 N. Lake Shore Drive, Suite 1400, Chicago, IL, 60611, USA. matthewjfeinstein@northwestern.edu.
          [2 ] University of Washington School of Medicine, Seattle, USA.
          [3 ] School of Public Health, University of Washington, Seattle, USA.
          [4 ] University of California-Los Angeles School of Medicine, Los Angeles, USA.
          [5 ] University of Alabama-Birmingham School of Medicine, Birmingham, USA.
          [6 ] Department of Medicine, University of California-San Diego Medical Center, San Diego, USA.
          [7 ] Johns Hopkins University, Baltimore, USA.
          [8 ] University of North Carolina School of Medicine, Chapel Hill, USA.
          [9 ] University of California-San Francisco School of Medicine, San Francisco, USA.
          [10 ] Mount Sinai School of Medicine, New York City, USA.
          [11 ] Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, 680 N. Lake Shore Drive, Suite 1400, Chicago, IL, 60611, USA.
          Article
          10.1186/s12916-019-1385-7
          10.1186/s12916-019-1385-7
          6668167
          31362721
          d4023bc2-0a15-49b7-b2a8-00c526ab65b5
          History

          Cardiovascular diseases,Multicenter study,Myocardial infarction,Mortality,Comorbidity,Epidemiology,Human immunodeficiency virus

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