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      The dynamics of COVID-19 with quarantined and isolation

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          Abstract

          In the present paper, we formulate a new mathematical model for the dynamics of COVID-19 with quarantine and isolation. Initially, we provide a brief discussion on the model formulation and provide relevant mathematical results. Then, we consider the fractal-fractional derivative in Atangana–Baleanu sense, and we also generalize the model. The generalized model is used to obtain its stability results. We show that the model is locally asymptotically stable if \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$\mathcal{R}_{0}<1$\end{document} . Further, we consider the real cases reported in China since January 11 till April 9, 2020. The reported cases have been used for obtaining the real parameters and the basic reproduction number for the given period, \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$\mathcal{R}_{0}\approx 6.6361$\end{document} . The data of reported cases versus model for classical and fractal-factional order are presented. We show that the fractal-fractional order model provides the best fitting to the reported cases. The fractional mathematical model is solved by a novel numerical technique based on Newton approach, which is useful and reliable. A brief discussion on the graphical results using the novel numerical procedures are shown. Some key parameters that show significance in the disease elimination from the society are explored.

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          A conceptual model for the outbreak of Coronavirus disease 2019 (COVID-19) in Wuhan, China with individual reaction and governmental action

          Highlights • For the ongoing novel coronavirus disease (CODID-19) outbreak in Wuhan, China, the Chinese government has implemented control measures such as city lockdown to mitigate the impact of the epidemic. • We model the outbreak in Wuhan with individual reaction and governmental action (holiday extension, city lockdown, hospitalisation and quarantine) based on some parameters of the 1918 influenza pandemic in London, United Kingdom. • We show the different effects of individual reaction and governmental action and preliminarily estimate the magnitude of these effects. • We also preliminarily estimate the time-varying reporting ratio.
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            Modelling the spread of COVID-19 with new fractal-fractional operators: Can the lockdown save mankind before vaccination?

            Highlights • New COVID-19 mathematical model with lock-down effect. • New fractal-fractional differentiation. • New fractal-fractional integration. • Numerical scheme based on Newton polynomial.
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              Modeling the impact of non-pharmaceutical interventions on the dynamics of novel coronavirus with optimal control analysis with a case study

              Highlights • A mathematical model for COVID-19 with non-pharmaceutical interventions are considered. • Real infected cases of Pakistan are considered to obtain the parameter estimations and model fitting. • Stability results are shown for the model. • The optimal control problem is formulated using optimal control theory. • Numerical results for the key parameters are given which can be regarded as the possible control of the disease.
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                Author and article information

                Contributors
                fatmawati@fst.unair.ac.id
                Journal
                Adv Differ Equ
                Adv Differ Equ
                Advances in Difference Equations
                Springer International Publishing (Cham )
                1687-1839
                1687-1847
                14 August 2020
                14 August 2020
                2020
                : 2020
                : 1
                : 425
                Affiliations
                [1 ]GRID grid.444812.f, ISNI 0000 0004 5936 4802, Informetrics Research Group, , Ton Duc Thang University, ; Ho Chi Minh City, Vietnam
                [2 ]GRID grid.444812.f, ISNI 0000 0004 5936 4802, Faculty of Mathematics and Statistics, , Ton Duc Thang University, ; Ho Chi Minh City, Vietnam
                [3 ]GRID grid.412219.d, ISNI 0000 0001 2284 638X, Faculty of Natural and Agricultural Sciences, , University of the Free State, ; Bloemfontien, South Africa
                [4 ]GRID grid.411508.9, ISNI 0000 0004 0572 9415, Department of Medical Research, , China Medical University Hospital, ; Taichung, Taiwan
                [5 ]GRID grid.412125.1, ISNI 0000 0001 0619 1117, Department of Mathematics, Faculty of Science, , King Abdulaziz University, ; P. O. Box 80203, Jeddah, 21589 Saudi Arabia
                [6 ]GRID grid.440745.6, ISNI 0000 0001 0152 762X, Department of Mathematics, Faculty of Science and Technology, , Universitas Airlangga, ; 60115 Surabaya, Indonesia
                Article
                2882
                10.1186/s13662-020-02882-9
                7427274
                32834821
                d2b4524b-8574-4d5b-b129-34f7f37d970b
                © The Author(s) 2020

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 12 June 2020
                : 4 August 2020
                Categories
                Research
                Custom metadata
                © The Author(s) 2020

                covid-19 model,quarantine and isolation,fractal-fractional model,estimation of the parameters,numerical results

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