Nick Astbury Consultant Ophthalmic Surgeon, Norfolk and Norwich University Hospital
NHS Trust, Colney Lane, Norwich NR4 7UY, UK.
Every eye surgeon has experienced – or will experience – that sinking feeling when
the posterior capsule is ruptured and vitreous comes forward into the anterior chamber.
At that moment everything changes, including the heart rate of the surgeon and the
possible outcome for the patient.
But all is not lost. If the theatre team are well prepared, the situation can be managed
calmly and professionally in order to achieve the best possible visual result.
It is most important to remove every trace of vitreous from the wound and anterior
chamber. Failure to achieve this increases the risks of leakage, of infection due
to a vitreous wick, or of vitreous traction that may lead to cystoid macular oedema
or retinal detachment.
In an ideal world, automated vitrectomy should be the procedure of choice to deal
with vitreous loss; however, if the equipment is unavailable, it may be necessary
to resort to the ‘sponge and scissors’ vitrectomy method.
Implanting an intraocular lens (IOL), although desirable, should not be undertaken
at any cost if it will involve further trauma to the eye.
It is worth mentioning that pressure from the speculum is often to blame for the difficulty
surgeons experience in dealing with capsular rupture and vitreous loss. Therefore,
it is always advisable to make sure that the speculum is not pressing on the eye.
Below, five ophthalmologists from around the world present their tips on managing
this complication. Their opinions and methods differ, depending upon individual circumstances
and available resources.
Vitrectomy parameters set on a phaco machine used to perform automated vitrectomy
after capsular rupture and vitreous loss. INDIA
A surgeon performs a vitrectomy after capsular rupture and vitreous loss. INDIA
Tanzania
Mark Wood Consultant Ophthalmologist, CCBRT Hospital, Box 23310, Dar es Salaam, Tanzania.
Email: markwood@cats-net.com
Capsular rupture is a dreaded complication of cataract surgery; it jeopardises the
chances of inserting a posterior lens and therefore obtaining the ideal optical correction
of the patient's aphakia after the operation. However, if this complication does occur,
do not panic: most cases can be salvaged.
Tip 1
Stop everything. Sit back and think. Get your vitrector ready while thinking. The
Guerder Vitron anterior vitrectomy machine is ideal and should be made available to
all cataract surgeons. You will have to perform an anterior vitrectomy. Try to preserve
as much capsule as possible while you do this.
Tip 2
After you have done a vitrectomy, if you are not sure how much capsule remains it
may be wise to close the incision and consider implanting a secondary IOL. Later,
you can use the slit lamp to visualise the remaining capsule and plan your operation.
Tip 3
If you have done a continuous curvilinear capsulorhexis, you should be able to insert
a lens in the sulcus, as the anterior rim of the capsule will hopefully still be there.
With a linear capsulotomy this may be possible as well. I usually insert a hard lens
into the sulcus and abandon any idea of using a foldable lens. If there is enough
capsule inferiorly, I use an Aurolab scleral fixation lens. This IOL has the advantage
of having a large optic of 6.5 mm which gives it added stability; it can be sutured
with 10-0 Prolene to the iris at the 12 o'clock position through the hole in the haptic.
This is not possible with small incision surgery, because you cannot suture the lens
to the iris down a tunnel incision.
Tip 4
If you have done small incision surgery, it is more difficult to manage vitreous loss.
In this circumstance, I would probably close the eye and implant a secondary IOL.
It is always preferable to implant a posterior lens. However, if this is not possible,
an anterior chamber lens is a good alternative. Do not forget to do an iridectomy.
I perform two iridectomies when placing an anterior lens.
Tip 5
In a patient with an only eye, do not forget that +10 aphakic correction spectacles
can give good vision; this is better than struggling to insert an imperfect IOL which
may cause more damage to the tissues.
India
Uday Gajiwala (left), Rajesh Patel, and others in the Sewa Rural Team Sewa Rural,
Jhagadia District, Bharuch, Gujarat 393 110, India.
Tip 1
If capsular rupture and vitreous loss occurs after complete removal of the lens matter,
perform a good anterior vitrectomy (an automated vitrectomy probe without in-built
irrigation is preferable).
To prevent extension of the tear, hydration of the vitreous, and flushing of the vitreous,
the cut rate of the vitrectomy machine should be high (up to 800 cuts per minute)
and the vacuum should be low (approximately 50 mmHg).
Tip 2
If capsular rupture and vitreous loss occurs while some lens matter remains, perform
a good automated anterior vitrectomy and cortex removal, ensuring aspiration of the
cortex towards the tear and not away from it. Dry aspiration is most suitable.
Tip 3
Complete removal of vitreous from the anterior chamber is indicated by a round pupil,
the falling back of the iris, and the formation of a single air bubble after air injection.
Tip 4
Special situations
If the capsular tear is in the inferior position, be careful because the IOL can drop
from the tear into the vitreous cavity.
If there is a bulge in the vitreous material, giving a systemic injection of mannitol
while the patient is on the operating table may help to reduce the pressure.
Performing a three-port pars plana vitrectomy. UK
Tip 5
Placement of the IOL
In the case of a posterior capsular tear involving less than a third of the periphery,
the IOL can be placed with the haptics positioned away from the tear; the stability
of the IOL should then be checked.
With a central tear and an adequate rim all the way around, a sulcus-fixated IOL can
be implanted. The IOL can be placed in front of the anterior capsule if the rhexis
is round and the rim is adequate in size. But if the support is less than adequate,
it may be necessary to place an anterior chamber IOL or a sclerally fixated IOL.
In all cases of posterior capsular tear, it is important to use an IOL with a large
optic size (>6.0 mm) and with a large overall diameter (>13.5 mm).
Always remember:
The importance of recognising the complication as early as possible cannot be overemphasised.
Do not panic, keep calm, keep to the basic rules.
No vitreous should be left in the iris plane or in front of it.
‘Sponge and scissors’ vitrectomy should be avoided if at all possible.
The placement of the IOL depends on the capsular support available – even if the anterior
capsule is available, a posterior chamber IOL can be implanted in the sulcus.
Try to do a primary IOL implant, whether it is an anterior chamber IOL or a sclerally
fixated IOL.
It is good practice to inform the patient of the complication.
China
Yi Chen People Eye Centre, Peking University People's Hospital, Beijing 100044, China.
Email: chenyi88888@vip.sina.com
Tip 1
Stop working as soon as you sense that there is a problem. Carefully remove the instrument
from the eye if possible. Remember that an abrupt shallowing of the anterior chamber
may extend the tear and that abrupt removal of the instrument may lead to lens material
falling into the vitreous. Inject viscoelastic fluid through the side-port incision,
if necessary, before removing instruments from the eye.
Tip 2
Maintain the anterior chamber and stabilise the remaining lens material. Filling the
anterior chamber with viscoelastic helps to maintain the anterior chamber and may
help to tamponade the anterior hyaloid face. Injecting viscoelastic below the remaining
lens material may stabilise it.
Tip 3
If possible, remove all remaining lens material. Enlarge the incision and extract
the nucleus with a loop. If the capsular rupture is small, the irrigation-aspiration
technique may be used to aspirate the remaining cortex. If the capsular rupture is
large and cortex is mixed with vitreous, an anterior vitrectomy may be used to remove
both the cortex and vitreous.
Tip 4
If vitreous loss has occurred, remove all vitreous from the anterior chamber and the
incision. A ‘sponge and scissors’ vitrectomy can be very useful if automated vitrectomy
instruments are not available; however, it is unlikely to remove all vitreous from
the anterior chamber. Automated vitrectomy is preferable.
Tip 5
Implant the IOL according to the situation. ‘In the bag’ placement is ideal. If there
is a large rupture of the posterior capsule, the surgeon may implant the IOL in the
ciliary sulcus. Once the IOL has been placed, gradually instil a miotic. Afterwards,
remove the viscoelastic with irrigation-aspiration. Raising the irrigation bottle
is important to avoid any shallowing of the anterior chamber; this will help prevent
further vitreous prolapse. You must pay careful attention. In particular, check the
pupil and wounds to ensure that all vitreous has been removed. Always check that the
wounds are watertight.
United Kingdom
Larry Benjamin Consultant Ophthalmic Surgeon, Department of Ophthalmology, Stoke Mandeville
Hospital, Mandeville Road, Aylesbury, Buckinghamshire, HP21 8AL, UK.
Tip 1
If vitreous loss is managed well, the outcome can be just as good as if it had not
happened. The first tip is early recognition that vitreous loss has taken place. The
implications of vitreous loss may vary, depending on the type of cataract surgery.
It tends to be a fairly expulsive event when it occurs during extracapsular surgery,
but it is less so during closed-chamber phacoemulsification. By recognising the event
early, steps can be taken to minimise further problems. Take time to sit back for
a minute and assess the situation carefully. Do not suddenly pull instruments out
of the eye – this may cause vitreoretinal traction.
Tip 2
Keep calm and ask for the vitrector in a quiet, level voice (as if you were simply
asking someone to pass the salt). Make sure the team environment stays calm and supportive.
You should learn how to set up and use the vitrector before a case of vitreous loss
has to be dealt with. This experience can be gained in a skills centre.
Tip 3
Use triamcinolone acetonide (Kenelog) to stain the vitreous in the anterior chamber
(this is an off-label use). A solution of 40 mg in 1 ml can be used for this purpose,
neat or diluted twice or three times its own volume with a balanced salt solution.
A gentle injection of the drug via a Rycroft cannula into the anterior chamber (Figure
1) will make the vitreous easier to see and help to guide you: you will be able to
see when all the vitreous has been removed from the wound and pupillary area (Figure
2). If some triamcinolone remains in the eye, it will have anti-inflammatory properties;
however, checks should be made postoperatively for a rise in intraocular pressure.
Figure 1
Triamcinolone acetonide is injected into the anterior chamber to stain the vitreous
and make it easier to see.
Figure 2
Using a vitrector. Note the vitreous which has been stained with triamcinolone acetonide.
Tip 4
Using a separate small wound for the vitrector prevents the main wound from becoming
oedematous and maintains an effective closed chamber. Use the vitrector at the maximum
cut rate (usually around 400 cuts per minute on an anterior vitrector) and make small
movements of the probe within the eye. This will minimise vitreoretinal traction during
the operation. It is a good idea to separate the infusion fluid from the vitrector
and to start the anterior vitrectomy with no fluid running. Keep the vacuum low during
this step. When the infusion is started, keep the flow rate low. An anterior chamber
maintainer is a very useful device for delivering the infusion fluid. This is placed
at the limbus and is self-retaining.
Tip 5
Postoperative follow-up is important. The patient will need to be told that a complication
has occurred and should be informed of the possible outcomes. A topical steroid, an
antibiotic, and a mydriatic should be used postoperatively and regular follow-up visits
should take place until the eye is quiet and further complications are ruled out or
managed. If you did not place an implant during the initial operation, you can make
arrangements to do this at a later date. Other forms of visual correction in the short
term (such as contact lenses) can be discussed. You should carefully inspect the retinal
periphery when the eye is quiet. The patient should be warned about the possible symptoms
of retinal detachment, cystoid macular oedema, and infection.
Nigeria
Sunday O Abuh Paediatric Ophthalmologist, ECWA Eye Hospital, PO Box 14, Kano, Nigeria.
Email: absund@yahoo.com
Tip 1
Vitreous loss may be inevitable in eyes that have undergone couching or in cases of
vitreous degeneration. However, in all cases, vitreous loss must be carefully managed
to prevent complications such as defective wound closure, high astigmatism, high or
low intraocular pressure, corneal oedema from endothelial touch, retinal detachment,
chronic inflammation, or cystoid macular oedema.
Tip 2
Management starts with good preoperative patient education to reduce the risk of patient
movement during surgery. Approximately 90–95% of our patients remain quiet during
surgery without any form of premedication.
Tip 3
Poor anaesthesia is a major contributing factor to vitreous loss. Good anaesthesia
must achieve good pain relief (analgesia) and immobilisation (akinesia) of the lids
and globe (page 14).
Tip 4
Avoid undue pressure on the eye from the fixation forceps, speculum, or lens expressor.
Avoid clumsy use of instruments inside the eye. Avoid creating too high a pressure
when injecting the irrigating fluid into the anterior chamber.
Tip 5
When forced to use the manual ‘sponge and scissors’ vitrectomy method:
Work with good magnification and illumination.
Use non-fragmenting cellulose sponges.
Touch the vitreous in the anterior chamber with a sponge tip and cut the vitreous
strands with sharp De Wecker's or Wescott's scissors.
Avoid excessive traction on the vitreous.
Repeat the procedure until all strands of vitreous are removed from the anterior chamber,
iris surface, and wound edges.
After removing the vitreous, sweep the iris surface with an iris repositor to check
whether there is residual vitreous. If present, the pupil may be distorted. Repeat
the procedure until the pupil becomes round.
A weak solution of pilocarpine (we use four drops of 4% pilocarpine in 2 ml of normal
saline solution) may be instilled into the anterior chamber to constrict the pupil
and keep the vitreous behind the iris.
Re-form the anterior chamber with air after wound closure to minimise vitreous entrapment
in the wound.