Prognostic Value of Glial Fibrillary Acidic Protein in Patients With Moderate and Severe Traumatic Brain Injury: A Systematic Review and Meta-Analysis.

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Abstract

Biomarkers have been suggested as potential prognostic predictors following a moderate or severe traumatic brain injury but their prognostic accuracy is still uncertain. The objective of this systematic review is to assess the ability of the glial fibrillary acidic protein to predict prognosis in patients with moderate or severe traumatic brain injury.

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Author and article information

Journal

Journal ID (iso-abbrev): Crit Care Med

Title: Critical care medicine

Publisher: Ovid Technologies (Wolters Kluwer Health)

ISSN (Electronic): 1530-0293

ISSN (Print): 0090-3493

Publication date (Electronic): June 2019

Volume: 47

Issue: 6

Affiliations

[1 ] CHU de Québec - Université Laval Research Center, Population Health and Optimal Health Practices Research Unit (Trauma - Emergency - Critical Care Medicine), Université Laval, Québec City, QC, Canada.

[2 ] Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Université Laval, Québec City, QC, Canada.

[3 ] Department of Medicine, Université Laval, Québec City, QC, Canada.

[4 ] Department of Haematology and Medical Oncology, University of Manitoba, Winnipeg, MB, Canada.

[5 ] Department of Social and Preventive Medicine, Université Laval, Québec City, QC, Canada.

[6 ] Department of Medicine, Division of Critical Care, University of Ottawa, Ottawa, ON, Canada.

[7 ] Center for Transfusion and Critical Care Research, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.

[8 ] Department of Molecular Biology, Medical Biochemistry and Pathology, Université Laval, Québec City, QC, Canada.

[9 ] Department of Family Medicine and Emergency Medicine, Université Laval, Québec City, QC, Canada.

[10 ] Research Center of l'Hôtel-Dieu de Lévis, CISSS de Chaudières-Appalaches, Lévis, QC, Canada.

[11 ] Department of Medicine, Université de Sherbrooke, Sherbrooke, QC, Canada.

[12 ] CHU de Sherbrooke Research Center, Sherbrooke, QC, Canada.

Article

DOI: 10.1097/CCM.0000000000003728

PubMed ID: 30889029

SO-VID: d26d1351-bc2c-4dd3-91db-7e0cf89953fb

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