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      Astaxanthin attenuates oxidative stress and inflammatory responses in complete Freund-adjuvant-induced arthritis in rats.

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          Abstract

          Astaxanthin (ATX), a natural xanthophyll carotenoid, has shown to exert significant protective effects against various diseases via its antioxidant and anti-inflammatory properties. However, its potential role in arthritis is still not reported. Therefore, the aim of the present study was to investigate the potential anti-arthritic properties of ATX against complete Freund's adjuvant (CFA)-induced arthritis rats.

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          Author and article information

          Journal
          Pharmacol Rep
          Pharmacological reports : PR
          Springer Science and Business Media LLC
          1734-1140
          1734-1140
          Feb 2020
          : 72
          : 1
          Affiliations
          [1 ] Pharmacology Division, University Institute of Pharmaceutical Sciences (UIPS), Panjab University, Chandigarh, 160014, India.
          [2 ] Pharmacology Division, University Institute of Pharmaceutical Sciences (UIPS), Panjab University, Chandigarh, 160014, India. dr_chopra_k@yahoo.com.
          [3 ] Pharmacology Research Laboratory, UGC Centre of Advanced Studies, University Institute of Pharmaceutical Sciences (UIPS), Panjab University, Chandigarh, 160014, India. dr_chopra_k@yahoo.com.
          Article
          10.1007/s43440-019-00022-z
          10.1007/s43440-019-00022-z
          32016833
          d1e58776-bb86-4ace-a4c6-16b1e9c83ed1
          History

          Inflammation,Anti-oxidant,Astaxanthin,Rheumatoid arthritis,Oxidative stress

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