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      Artificial Intelligence to Detect Papilledema from Ocular Fundus Photographs

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      New England Journal of Medicine
      Massachusetts Medical Society

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          Abstract

          Nonophthalmologist physicians do not confidently perform direct ophthalmoscopy. The use of artificial intelligence to detect papilledema and other optic-disk abnormalities from fundus photographs has not been well studied.

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          Most cited references35

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          Deep learning.

          Deep learning allows computational models that are composed of multiple processing layers to learn representations of data with multiple levels of abstraction. These methods have dramatically improved the state-of-the-art in speech recognition, visual object recognition, object detection and many other domains such as drug discovery and genomics. Deep learning discovers intricate structure in large data sets by using the backpropagation algorithm to indicate how a machine should change its internal parameters that are used to compute the representation in each layer from the representation in the previous layer. Deep convolutional nets have brought about breakthroughs in processing images, video, speech and audio, whereas recurrent nets have shone light on sequential data such as text and speech.
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            Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs.

            Deep learning is a family of computational methods that allow an algorithm to program itself by learning from a large set of examples that demonstrate the desired behavior, removing the need to specify rules explicitly. Application of these methods to medical imaging requires further assessment and validation.
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              Machine Learning in Medicine

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                Author and article information

                Journal
                New England Journal of Medicine
                N Engl J Med
                Massachusetts Medical Society
                0028-4793
                1533-4406
                April 14 2020
                Affiliations
                [1 ]From the Singapore National Eye Center (D.M., D.T., S.S., C.-Y.C., T.Y.W.), Singapore Eye Research Institute (D.M., R.P.N., D.T., C.V., S.S., C.-Y.C., T.Y.W.), Duke–NUS Medical School (D.M., R.P.N., D.T., S.S., C.-Y.C., T.Y.W.), Institute of High Performance Computing, Agency for Science, Technology, and Research (J.Z., X.X., Y.L.), and Yong Loo Lin School of Medicine, National University of Singapore (S.S., T.Y.W.) — all in Singapore; Farabi Eye Hospital, Tehran University of Medical Science, Tehran,...
                Article
                10.1056/NEJMoa1917130
                32286748
                d13c81e3-4686-41a9-b75a-0225bae391c2
                © 2020

                http://www.nejmgroup.org/legal/terms-of-use.htm

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