Clinical impact of the presence of macrophages in endomyocardial biopsies of patients with dilated cardiomyopathy.

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Abstract

Dilated cardiomyopathy (DCM) is the most common cardiomyopathy and causes left ventricular enlargement and contractile dysfunction, with a poor prognosis. The mechanisms underlying the disease process have not been precisely identified, but recent evidence has suggested that the activation of myocardial inflammation is involved in the deterioration associated with the condition.

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Author and article information

Journal

Journal ID (iso-abbrev): Eur. J. Heart Fail.

Title: European journal of heart failure

Publisher: Wiley

ISSN (Electronic): 1879-0844

ISSN (Print): 1388-9842

Publication date (Electronic): April 2017

Volume: 19

Issue: 4

Affiliations

[1 ] Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka, 565-8565, Japan.

[2 ] Department of Pathology, National Cerebral and Cardiovascular Center, Osaka, Japan.

[3 ] Department of Transplantation, National Cerebral and Cardiovascular Center, Osaka, Japan.

[4 ] Department of Cardio-Renal Medicine and Hypertension, Nagoya City University, Japan.

Article

DOI: 10.1002/ejhf.767

PubMed ID: 28217949

SO-VID: d13c2985-aaeb-4d2a-acff-8d11972aa1b0

History

Keywords: Prognosis,Dilated cardiomyopathy,Fibrosis,Inflammation,Macrophage

Data availability:

Keywords: Prognosis, Dilated cardiomyopathy, Fibrosis, Inflammation, Macrophage

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