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Hormone replacement therapy and mid-term implant survival following knee or hip arthroplasty for osteoarthritis: a population-based cohort study
February 05 2015
January 22 2014
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Abstract
Osteolysis and subsequent prosthesis loosening is the most common cause for revision
following total knee arthroplasty (TKA) or total hip arthroplasty (THA). Hormone replacement
therapy (HRT) could reduce osteolysis through its antiresorptive effects. We studied
whether HRT use is associated with reduced revision rates in a community-based cohort
of women undergoing TKA or THA for osteoarthritis.