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Extended lymph-node dissection for gastric cancer.
J J Bonenkamp
1 ,
J Hermans ,
M Sasako ,
C J van de Velde ,
K Welvaart ,
I Songun ,
S Meyer ,
J T Plukker ,
P Van Elk ,
H Obertop ,
D J Gouma ,
J J van Lanschot ,
C W Taat ,
P W de Graaf ,
M F von Meyenfeldt ,
H Tilanus
Mar 25 1999
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Abstract
Curative resection is the treatment of choice for gastric cancer, but it is unclear whether this operation should include an extended (D2) lymph-node dissection, as recommended by the Japanese medical community, or a limited (D1) dissection. We conducted a randomized trial in 80 Dutch hospitals in which we compared D1 with D2 lymph-node dissection for gastric cancer in terms of morbidity, postoperative mortality, long-term survival, and cumulative risk of relapse after surgery.