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      Preliminary findings of alterations in serum alkaline phosphatase activity in chickens during coccidial infections

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      Journal of Comparative Pathology
      Elsevier BV

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          Abstract

          Two-week-old broiler chickens were inoculated orally with various doses of avian Eimeria that infect different sections of the intestine. The coccidia used were E. acervulina (duodenum), E. maxima (jejunum), E. brunetti (ileum) and E. tenella (caecum). The measurements evaluated were weight gains, intestinal lesion scores and changes in serum alkaline phosphatase (SAP) activity 6 days after infection. SAP activity was inversely proportional to both oocyst dose and gross intestinal lesion score, and directly proportional to weight gains with infections of E. acervulina, E. maxima and E. tenella. However, no significant changes in the SAP activity were found in those birds infected with E. brunetti. Taken together, the data suggest that SAP activity may be a sensitive marker of the pathogenesis of certain coccidial infections, especially in the duodenum, jejunum and caecum, that may be used as an additional factor in evaluating coccidial control measures.

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          Author and article information

          Journal
          Journal of Comparative Pathology
          Journal of Comparative Pathology
          Elsevier BV
          00219975
          February 1993
          February 1993
          : 108
          : 2
          : 113-119
          Article
          10.1016/S0021-9975(08)80215-0
          8473563
          cff57e73-494d-4d92-8077-5158d13b0734
          © 1993

          https://www.elsevier.com/tdm/userlicense/1.0/

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