ORIENTATION: Safety compliance remains a major issue in the South African mining industry. This article explores the roles of specific work-related job and attitudinal variables in predicting compliance. RESEARCH PURPOSE:The objective of this study was to investigate the relationship of work stress, job insecurity, satisfaction and commitment to safety compliance in a mine. MOTIVATION FOR THE STUDY: The study aims to predict safety compliance through work-related variables in order to manage safety better. RESEARCH DESIGN, APPROACH AND METHOD: The researchers used a cross-sectional survey design with a convenience sample (n = 158). They distributed a survey booklet. It included a biographical questionnaire, scales for job insecurity, satisfaction, affective organisational commitment, workplace accidents and safety compliance as well as a work stress measure that comprised dimensions of role clarity, conflict and overload. MAIN FINDINGS: The results showed that work stress and job insecurity had a negative relationship with safety compliance. The researchers found that only job satisfaction was a significant predictor of safety. PRACTICAL/MANAGERIAL IMPLICATIONS: Although exploratory, this study suggests that promoting job satisfaction may improve safety compliance whilst job stress and job insecurity also relate negatively to safety compliance. CONTRIBUTION/VALUE-ADD: This study shows that job satisfaction is more important than organisational commitment, job security and work stress for predicting safety compliance.