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      A distinctive epigenetic ageing profile in human granulosa cells.

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          Abstract

          Does women's age affect the DNA methylation (DNAm) profile differently in mural granulosa cells (MGCs) from other somatic cells?

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          Author and article information

          Journal
          Hum Reprod
          Human reproduction (Oxford, England)
          Oxford University Press (OUP)
          1460-2350
          0268-1161
          June 01 2020
          : 35
          : 6
          Affiliations
          [1 ] Department of Obstetrics and Gynaecology, Department of Reproductive Medicine, Copenhagen University Hospital Herlev, Herlev, Denmark.
          [2 ] DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
          [3 ] Epigenetics Programme, Babraham Institute, Cambridge, UK.
          [4 ] Department of Obstetrics and Gynaecology, The Fertility Clinic, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
          [5 ] Stork IVF Clinic A/S Copenhagen, VivaNeo Fertility Clinics, Copenhagen, Denmark.
          [6 ] Reproductive Medicine Centre, Skåne University Hospital, Malmoe, UK.
          [7 ] Medical Research Council Epidemiology Unit, University of Cambridge Addenbrooke's Hospital, Cambridge, UK.
          [8 ] Department of Genetics, University of Cambridge, Cambridge, UK.
          [9 ] Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
          [10 ] Centre for Trophoblast Research, University of Cambridge, Cambridge, UK.
          Article
          5848691
          10.1093/humrep/deaa071
          32474592
          ce9143aa-e691-4129-9b87-2015ffee8894
          History

          age,epigenetics,granulosa cells,reproduction,DNA methylation

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