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      Assessing inattention and impulsivity in children during the Go/NoGo task.

      The British Journal of Developmental Psychology
      Analysis of Variance, Attention, physiology, Attention Deficit Disorder with Hyperactivity, diagnosis, physiopathology, Caregivers, Child, Child Behavior, Child Behavior Disorders, Cognition, Faculty, Female, Humans, Impulse Control Disorders, Impulsive Behavior, Male, Neuropsychological Tests, Psychiatric Status Rating Scales, Psychomotor Performance, Questionnaires, Reaction Time, Sex Factors

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          Abstract

          Behavioural performance in the Go/NoGo task was compared with caregiver and teacher reports of inattention and hyperactivity-impulsivity in 1,151 children (N = 557 boys; N = 594 girls) age 9- 10-years-old. Errors of commission (NoGo errors) were significantly correlated with symptom counts of hyperactivity-impulsivity, while errors of omission (Go errors) were significantly correlated with symptom counts for inattention in both caregiver and teacher reports. Cross-correlations were also evident, however, such that errors of commission were related to inattention symptoms, and errors of omission were related to hyperactivity-impulsivity. Moreover, hyperactivity-impulsivity and inattention symptoms were highly intercorrelated in both caregiver (r = .52) and teacher reports (r = .70), while errors of commission and omission were virtually uncorrelated in the Go/NoGo task (r = .06). The results highlight the difficulty in disentangling hyperactivity-impulsivity and inattention in questionnaires, and suggest that these constructs may be more clearly distinguished in laboratory measures such as the Go/NoGo task.

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          Differential heritability of adult and juvenile antisocial traits.

          Studies of adult antisocial behavior or criminality usually find genetic factors to be more important than the family environment, whereas studies of delinquency find the family environment to be more important. We compared DSM-III-R antisocial personality disorder symptoms before vs after the age of 15 years within a sample of twins, rather than comparing across studies. We administered the Diagnostic Interview Schedule Version III-revised by telephone to 3226 pairs of male twins from the Vietnam Era Twin Registry. Biometrical modeling was applied to each symptom of antisocial personality disorder and summary measures of juvenile and adult symptoms. Five juvenile symptoms were significantly heritable, and five were significantly influenced by the shared environment. Eight adult symptoms were significantly heritable, and one was significantly influenced by the shared environment. The shared environment explained about six times more variance in juvenile anti-social traits than in adult traits. Shared environmental influences on adult antisocial traits overlapped entirely with those on juvenile traits. Additive genetic factors explained about six times more variance in adult vs juvenile traits. The juvenile genetic determinants overlapped completely with genetic influences on adult traits. The unique environment (plus measurement error) explained the largest proportion of variance in both juvenile and adult antisocial traits. Characteristics of the shared or family environment that promote antisocial behavior during childhood and early adolescence also promote later antisocial behavior, but to a much lesser extent. Genetic causal factors are much more prominent for adult than for juvenile antisocial traits.
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            Prevalence of ADHD and comorbid disorders among elementary school children screened for disruptive behavior.

            In the context of a school-based prevention of conduct disorder program, 7,231 first- through fourth-grade children were screened for cross-setting disruptive behavior. Frequencies of DSM-III-R psychiatric disorders and patterns of comorbidity were assessed. We also examined the association of psychiatric diagnosis with child and parent characteristics to determine differential risk based on diagnostic subgroups. Attention deficit hyperactivity disorder (ADHD) and oppositional-defiant disorder (ODD) were the most frequent diagnoses. Mood and anxiety disorders were infrequent as single diagnoses. Patterns of comorbidity demonstrated that both externalizing and internalizing disorders commonly cooccurred with ADHD. More severe degrees of psychopathology and psychosocial risk accrued to the subgroup of youths with ADHD plus a comorbid externalizing disorder.
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              Psychometric properties of impulsivity measures: temporal stability, validity and factor structure.

              Temporal stability, discriminant validity, and factor structure of an array of performance measures of impulsivity was assessed within samples of normal (N = 48) and behaviorally disordered children (N = 88) ages 6-16 (126 M, 10 F; mean age = 10.57 years; SD = 2.13). Using a relatively conservative standard for adequate temporal stability, 31% of the variables derived from these measures met criterion. Of these, 83% were able to discriminate groups after partialling out the effects of intellectual aptitude and age. Factor analysis yielded a two-factor solution interpreted as representing cognitive (inhibitory control) and motivational (insensitivity to punishment/nonreward) components of impulsivity.
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