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      An improved deep learning approach and its applications on colonic polyp images detection

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          Abstract

          Background

          Colonic polyps are more likely to be cancerous, especially those with large diameter, large number and atypical hyperplasia. If colonic polyps cannot be treated in early stage, they are likely to develop into colon cancer. Colonoscopy is easily limited by the operator’s experience, and factors such as inexperience and visual fatigue will directly affect the accuracy of diagnosis. Cooperating with Hunan children’s hospital, we proposed and improved a deep learning approach with global average pooling (GAP) in colonoscopy for assisted diagnosis. Our approach for assisted diagnosis in colonoscopy can prompt endoscopists to pay attention to polyps that may be ignored in real time, improve the detection rate, reduce missed diagnosis, and improve the efficiency of medical diagnosis.

          Methods

          We selected colonoscopy images from the gastrointestinal endoscopy room of Hunan children’s hospital to form the colonic polyp datasets. And we applied the image classification method based on Deep Learning to the classification of Colonic Polyps. The classic networks we used are VGGNets and ResNets. By using global average pooling, we proposed the improved approaches: VGGNets-GAP and ResNets-GAP.

          Results

          The accuracies of all models in datasets exceed 98%. The TPR and TNR are above 96 and 98% respectively. In addition, VGGNets-GAP networks not only have high classification accuracies, but also have much fewer parameters than those of VGGNets.

          Conclusions

          The experimental results show that the proposed approach has good effect on the automatic detection of colonic polyps. The innovations of our method are in two aspects: (1) the detection accuracy of colonic polyps has been improved. (2) our approach reduces the memory consumption and makes the model lightweight. Compared with the original VGG networks, the parameters of our VGG19-GAP networks are greatly reduced.

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          Most cited references25

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          Deep Residual Learning for Image Recognition

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            Comparative Validation of Polyp Detection Methods in Video Colonoscopy: Results From the MICCAI 2015 Endoscopic Vision Challenge

            Colonoscopy is the gold standard for colon cancer screening though some polyps are still missed, thus preventing early disease detection and treatment. Several computational systems have been proposed to assist polyp detection during colonoscopy but so far without consistent evaluation. The lack of publicly available annotated databases has made it difficult to compare methods and to assess if they achieve performance levels acceptable for clinical use. The Automatic Polyp Detection sub-challenge, conducted as part of the Endoscopic Vision Challenge (http://endovis.grand-challenge.org) at the international conference on Medical Image Computing and Computer Assisted Intervention (MICCAI) in 2015, was an effort to address this need. In this paper, we report the results of this comparative evaluation of polyp detection methods, as well as describe additional experiments to further explore differences between methods. We define performance metrics and provide evaluation databases that allow comparison of multiple methodologies. Results show that convolutional neural networks are the state of the art. Nevertheless, it is also demonstrated that combining different methodologies can lead to an improved overall performance.
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              Application of convolutional neural network in the diagnosis of the invasion depth of gastric cancer based on conventional endoscopy

              According to guidelines, endoscopic resection should only be performed for patients whose early gastric cancer invasion depth is within the mucosa or submucosa of the stomach regardless of lymph node involvement. The accurate prediction of invasion depth based on endoscopic images is crucial for screening patients for endoscopic resection. We constructed a convolutional neural network computer-aided detection (CNN-CAD) system based on endoscopic images to determine invasion depth and screen patients for endoscopic resection.
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                Author and article information

                Contributors
                wangwei@csust.edu.cn
                mfxgz123@163.com
                wangxin@csust.edu.cn
                Journal
                BMC Med Imaging
                BMC Med Imaging
                BMC Medical Imaging
                BioMed Central (London )
                1471-2342
                22 July 2020
                22 July 2020
                2020
                : 20
                : 83
                Affiliations
                [1 ]GRID grid.440669.9, ISNI 0000 0001 0703 2206, School of Computer and Communication Engineering, , Changsha University of Science and Technology, ; Changsha, 410114 China
                [2 ]GRID grid.440223.3, Hunan Children’s Hospital, ; Changsha, 410000 China
                Author information
                http://orcid.org/0000-0002-2298-3429
                Article
                482
                10.1186/s12880-020-00482-3
                7374886
                32698839
                cd437370-138b-48de-a298-e058bc9c035a
                © The Author(s) 2020

                Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

                History
                : 7 January 2020
                : 8 July 2020
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100009000, National Defense Pre-Research Foundation of China;
                Award ID: 7301506
                Funded by: FundRef http://dx.doi.org/10.13039/501100001809, National Natural Science Foundation of China;
                Award ID: 61070040
                Funded by: FundRef http://dx.doi.org/10.13039/100014472, Scientific Research Foundation of Hunan Provincial Education Department;
                Award ID: 17C0043
                Award Recipient :
                Funded by: Natural Science Foundation of Hunan Province (CN)
                Award ID: 2019JJ80105
                Award Recipient :
                Funded by: Clinical Medical technology Innovation and Guidance Project of Hunan Province
                Award ID: 2018SK5040
                Award Recipient :
                Categories
                Technical Advance
                Custom metadata
                © The Author(s) 2020

                Radiology & Imaging
                colonic polyps,deep learning,convolutional neural networks,global average pooling

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