[1
]ISNI 0000 0000 9320 7537, GRID grid.1003.2, Institute for Molecular Bioscience, , The University of Queensland, ; Brisbane, Queensland 4072 Australia
[2
]ISNI 0000000121901201, GRID grid.83440.3b, Institute of Cardiovascular Science, , University College London, ; London, UK
[3
]ISNI 0000000121901201, GRID grid.83440.3b, British Heart Foundation Research Accelerator, , University College London, ; London, UK
[4
]ISNI 0000000121901201, GRID grid.83440.3b, Institute of Health Informatics, , University College London, ; London, UK
[5
]GRID grid.66859.34, Program in Medical and Population Genetics, , The Broad Institute of MIT and Harvard, ; Cambridge, MA USA
[6
]Department of Cardiology, University Medical Center Groningen, University of Groningen,
Groningen, The Netherlands
[7
]ISNI 0000 0004 0367 5222, GRID grid.475010.7, Section of Computational Biomedicine, Department of Medicine, , Boston University School of Medicine, ; Boston, MA USA
[8
]ISNI 0000 0004 1936 7558, GRID grid.189504.1, National Heart, , Lung, and Blood Institute’s and Boston University’s Framingham Heart Study, ; Framingham, MA USA
[9
]deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland
[10
]ISNI 0000000121901201, GRID grid.83440.3b, Health Data Research UK London, , University College London, ; London, UK
[11
]ISNI 0000 0004 1937 0626, GRID grid.4714.6, Cardiovascular Medicine unit, Department of Medicine Solna, , Karolinska Institute, ; Stockholm, Sweden
[12
]ISNI 0000 0000 8800 7493, GRID grid.410513.2, Pfizer Worldwide Research & Development, ; 1 Portland St, Cambridge, MA USA
[13
]ISNI 0000 0004 1936 8972, GRID grid.25879.31, Penn Cardiovascular Institute, Perelman School of Medicine, , University of Pennsylvania, ; Philadelphia, PA USA
[14
]ISNI 0000 0001 2113 8111, GRID grid.7445.2, Department of Epidemiology and Biostatistics, , Imperial College London, St Mary’s Campus, ; London, W2 1PG UK
[15
]ISNI 0000 0001 2113 8111, GRID grid.7445.2, MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics,
, Imperial College London, St Mary’s Campus, ; London, W2 1PG UK
[16
]ISNI 0000 0001 0930 2361, GRID grid.4514.4, Department of Clinical Sciences, , Lund University, ; Malmö, Sweden
[17
]ISNI 0000 0004 0646 7402, GRID grid.411646.0, Department of Cardiology, , Herlev Gentofte Hospital, ; Herlev Ringvej 57, 2650 Herlev, Denmark
[18
]ISNI 0000 0004 0386 9924, GRID grid.32224.35, Center for Genomic Medicine, , Massachusetts General Hospital, ; Boston, MA USA
[19
]ISNI 0000 0004 0386 9924, GRID grid.32224.35, Cardiovascular Research Center, , Massachusetts General Hospital, ; Boston, MA USA
[20
]ISNI 0000 0004 1937 0626, GRID grid.4714.6, Department of Neurobiology, Care Sciences and Society/ Section of Family Medicine
and Primary Care, , Karolinska Institutet, ; Stockholm, Sweden
[21
]ISNI 0000 0001 0304 6002, GRID grid.411953.b, School of Health and Social Sciences, , Dalarna University, ; Falun, Sweden
[22
]Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY 10591 USA
[23
]ISNI 0000000122986657, GRID grid.34477.33, Department of Biostatistics, , University of Washington, ; Seattle, WA USA
[24
]ISNI 0000000122986657, GRID grid.34477.33, Department of Medicine, University of Washington, ; Seattle, WA USA
[25
]ISNI 0000 0004 0441 5844, GRID grid.412162.2, Division of Cardiology, Department of Medicine, , Emory University Medical Center, ; Atlanta, GA USA
[26
]ISNI 0000 0000 9206 2401, GRID grid.267308.8, Department of Epidemiology, Human Genetics, and Environmental Sciences, , The University of Texas School of Public Health, ; Houston, Texas USA
[27
]Department of Molecular and Functional Genomics, Geisinger, Danville, PA USA
[28
]ISNI 0000 0004 0378 8294, GRID grid.62560.37, Division of Preventive Medicine, , Brigham and Women’s Hospital, ; Boston, MA 02215 USA
[29
]ISNI 000000041936754X, GRID grid.38142.3c, Harvard Medical School, ; Boston, MA 02115 USA
[30
]ISNI 0000 0004 1937 0626, GRID grid.4714.6, Department of Medical Epidemiology and Biostatistics, , Karolinska Institutet, ; Stockholm, Sweden
[31
]ISNI 0000 0004 0439 2056, GRID grid.418424.f, Novartis Institutes for Biomedical Research, ; Cambridge, MA USA
[32
]ISNI 0000 0004 1936 8470, GRID grid.10025.36, Department of Biostatistics, , University of Liverpool, ; Liverpool, UK
[33
]ISNI 0000 0001 2190 4373, GRID grid.7700.0, Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology,
Rheumatology), Medical Faculty of Mannheim, , University of Heidelberg, ; Heidelberg, Germany
[34
]ISNI 0000000121901201, GRID grid.83440.3b, The National Institute for Health Research University College London Hospitals Biomedical
Research Centre, , University College London, ; London, UK
[35
]ISNI 0000 0004 5903 3632, GRID grid.499548.d, The Alan Turing Institute, ; London, United Kingdom
[36
]Division of Molecular & Clinical Medicine, University of Dundee, Ninewells Hospital
and Medical School, Dundee, DD1 9SY UK
[37
]GRID grid.5603.0, Department of Internal Medicine B, , University Medicine Greifswald, ; Greifswald, Germany
[38
]DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald,
Germany
[39
]ISNI 0000000419368657, GRID grid.17635.36, Cardiovascular Division, Department of Medicine, , University of Minnesota, ; Minneapolis, MN USA
[40
]ISNI 0000 0004 0472 2713, GRID grid.418961.3, Regeneron Pharmaceuticals, Cardiovascular Research, ; 777 Old Saw Mill River Road, Tarrytown, NY 10591 USA
[41
]ISNI 0000 0001 0943 7661, GRID grid.10939.32, Estonian Genome Center, Institute of Genomics, , University of Tartu, ; Tartu, 51010 Estonia
[42
]ISNI 0000 0001 2193 314X, GRID grid.8756.c, Robertson Center for Biostatistics, , University of Glasgow, ; Glasgow, UK
[43
]ISNI 000000040459992X, GRID grid.5645.2, Department of Epidemiology, , Erasmus University Medical Center, ; Rotterdam, The Netherlands
[44
]GRID grid.5603.0, Institute for Community Medicine, , University Medicine Greifswald, ; Greifswald, Germany
[45
]ISNI 0000 0004 1936 9457, GRID grid.8993.b, Department of Public Health and Caring Sciences, Geriatrics, , Uppsala University, ; Uppsala, 75185 Sweden
[46
]ISNI 0000 0001 2175 4264, GRID grid.411024.2, Department of Medicine, Division of Cardiology, , University of Maryland School of Medicine, ; Baltimore, MD USA
[47
]ISNI 0000 0004 0640 0021, GRID grid.14013.37, School of Engineering and Natural Sciences, , University of Iceland, ; 101 Reykjavik, Iceland
[48
]ISNI 0000 0004 1936 8294, GRID grid.214572.7, Division of Cardiovascular Medicine, , University of Iowa Carver College of Medicine, ; Iowa City, IA USA
[49
]ISNI 0000 0004 0407 1981, GRID grid.4830.f, Department of Genetics, University Medical Center Groningen, , University of Groningen, ; Groningen, The Netherlands
[50
]GRID grid.411737.7, Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, ; Utrecht, The Netherlands
[51
]ISNI 0000000419368956, GRID grid.168010.e, Department of Medicine, Division of Cardiovascular Medicine, , Stanford University School of Medicine, ; Stanford, CA 94305 USA
[52
]ISNI 0000000419368956, GRID grid.168010.e, Stanford Cardiovascular Institute, , Stanford University, ; Stanford, CA 94305 USA
[53
]ISNI 0000 0004 1936 9457, GRID grid.8993.b, Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory,
, Uppsala University, ; Uppsala, Sweden
[54
]ISNI 0000000419368956, GRID grid.168010.e, Stanford Diabetes Research Center, , Stanford University, ; Stanford, CA 94305 USA
[55
]ISNI 0000000089452978, GRID grid.10419.3d, Department of Cardiology, , Leiden University Medical Center, ; Leiden, The Netherlands
[56
]ISNI 0000000089452978, GRID grid.10419.3d, Einthoven Laboratory for Experimental Vascular Medicine, , LUMC, ; Leiden, The Netherlands
[57
]ISNI 0000000121885934, GRID grid.5335.0, Department of Public Health and Primary Care, , University of Cambridge, ; Cambridge, CB2 0QQ UK
[58
]GRID grid.475435.4, Department of Cardiology, , Copenhagen University Hospital Rigshospitalet, ; Copenhagen, Denmark
[59
]ISNI 0000 0004 0400 6581, GRID grid.412925.9, Department of Cardiovascular Sciences, , University of Leicester and NIHR Leicester Biomedical Research Centre, Glenfield Hospital,
; Leicester, UK
[60
]ISNI 0000000121885934, GRID grid.5335.0, MRC Epidemiology Unit, Institute of Metabolic Science, , University of Cambridge School of Clinical Medicine, ; Cambridge, CB2 0QQ UK
[61
]ISNI 0000 0004 1936 9457, GRID grid.8993.b, Department of Medical Sciences, , Uppsala University, ; Uppsala, Sweden
[62
]ISNI 0000 0004 1936 8948, GRID grid.4991.5, Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery,
, University of Oxford, ; Oxford, UK
[63
]ISNI 0000 0004 1936 8948, GRID grid.4991.5, Wellcome Trust Centre for Human Genetics, , University of Oxford, ; Oxford, UK
[64
]ISNI 0000 0004 1936 8294, GRID grid.214572.7, Division of Cardiovascular Medicine and Abboud Cardiovascular Research Center, , University of Iowa, ; Iowa City, IA USA
[65
]Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany
[66
]ISNI 0000 0000 8988 2476, GRID grid.11598.34, Clinical Institute of Medical and Chemical Laboratory Diagnostics, , Medical University of Graz, ; Graz, Austria
[67
]Department of Internal Medicine, Clinical Sciences, Lund University and Skåne University
Hospital, Malmö, Sweden
[68
]ISNI 0000 0001 2264 7217, GRID grid.152326.1, Vanderbilt University School of Medicine, ; Nashville, TN USA
[69
]ISNI 0000 0004 1936 7988, GRID grid.4305.2, Usher Institute of Population Health Sciences and Informatics, , University of Edinburgh, ; Edinburgh, United Kingdom
[70
]ISNI 0000 0000 9259 8492, GRID grid.22937.3d, Department of Internal Medicine II, Division of Cardiology, , Medical University of Vienna, ; Vienna, Austria
[71
]ISNI 0000 0001 1013 0499, GRID grid.14758.3f, National Institute for Health and Welfare, ; Helsinki, Finland
[72
]ISNI 0000 0004 0628 215X, GRID grid.410552.7, Department of Medicine, , Turku University Hospital and University of Turku, ; Turku, Finland
[73
]ISNI 0000 0004 0378 8294, GRID grid.62560.37, TIMI Study Group, Cardiovascular Division, Brigham and Women’s Hospital, ; Boston, MA USA
[74
]ISNI 000000040459992X, GRID grid.5645.2, Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, , Erasmus University Medical Center, ; Rotterdam, The Netherlands
[75
]ISNI 0000000122986657, GRID grid.34477.33, Department of Medicine, Epidemiology, and Health Services, , University of Washington, ; Seattle, WA USA
[76
]ISNI 0000 0004 0615 7519, GRID grid.488833.c, Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington,
; Seattle, WA USA
[77
]The Institute for Translational Genomics and Population Sciences, Departments of Pediatrics
and Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center,
Torrance, CA USA
[78
]Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht,
University of Utrecht, Utrecht, The Netherlands
[79
]ISNI 0000 0001 0650 7433, GRID grid.412689.0, Division of Cardiology, Department of Medicine, , University of Pittsburgh Medical Center and VA Pittsburgh HCS, ; Pittsburgh, PA USA
[80
]ISNI 0000000122986657, GRID grid.34477.33, Department of Epidemiology, , University of Washington, ; Seattle, WA USA
[81
]Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs
Office of Research & Development, Seattle, WA USA
[82
]Department of Clinical Biochemistry, Copenhagen University Hospital, Herlev and Gentofte,
København, Denmark
[83
]ISNI 0000 0001 2193 314X, GRID grid.8756.c, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and
Life Sciences, , University of Glasgow, ; Glasgow, United Kingdom
[84
]Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet,
Stockholm, Sweden
[85
]ISNI 0000 0000 8986 2221, GRID grid.416648.9, Department of Cardiology, , Södersjukhuset, ; Stockholm, Sweden
[86
]ISNI 0000 0001 0157 6501, GRID grid.239844.0, Institute for Translational Genomics and Population Sciences, LABiomed and Departments
of Pediatrics at Harbor-UCLA Medical Center, ; Torrance, CA 90502 USA
[87
]ISNI 0000 0000 9894 0842, GRID grid.410540.4, Division of Cardiology, Department of Internal Medicine, Landspitali, , National University Hospital of Iceland, Hringbraut, ; 101 Reykjavik, Iceland
[88
]ISNI 0000 0004 0640 0021, GRID grid.14013.37, Faculty of Medicine, Department of Medicine, , University of Iceland, ; Saemundargata 2, 101, Reykjavik, Iceland
[89
]ISNI 0000 0004 0646 7349, GRID grid.27530.33, Department of Epidemiology and Biostatistics, , Aalborg University Hospital, ; Aalborg, Denmark
[90
]ISNI 0000 0004 0646 7349, GRID grid.27530.33, Department of Health, Science and Technology, , Aalborg University Hospital, ; Aalborg, Denmark
[91
]ISNI 0000 0004 0646 7349, GRID grid.27530.33, Departments of Cardiology, , Aalborg University Hospital, ; Aalborg, Denmark
[92
]ISNI 0000000089452978, GRID grid.10419.3d, Section of Gerontology and Geriatrics, Department of Internal Medicine, , Leiden University Medical Center, ; Leiden, The Netherlands
[93
]Translational and Clinical Research, Servier Cardiovascular Center for Therapeutic
Innovation, 50 rue Carnot, 92284 Suresnes, France
[94
]ISNI 000000040459992X, GRID grid.5645.2, Department of Internal Medicine, Erasmus MC, , University Medical Center Rotterdam, ; Rotterdam, The Netherlands
[95
]GRID grid.5603.0, Interfaculty Institute for Genetics and Functional Genomics, , University Medicine Greifswald, ; Greifswald, Germany
[96
]ISNI 0000 0004 0393 4335, GRID grid.418019.5, Human Genetics, GlaxoSmithKline, ; Collegeville, PA USA
[97
]ISNI 0000 0001 1545 0811, GRID grid.412332.5, Division of Cardiovascular Medicine, Department of Internal Medicine, , The Ohio State University Medical Center, ; Columbus, OH USA
[98
]Université de Lorraine, CHU de Nancy, Inserm and INI-CRCT (F-CRIN), Institut Lorrain
du Coeur et des Vaisseaux, 54500 Vandoeuvre Lès, Nancy France
[99
]ISNI 0000 0001 2193 314X, GRID grid.8756.c, BHF Cardiovascular Research Centre, , University of Glasgow, ; Glasgow, United Kingdom
[100
]ISNI 0000 0000 9320 7537, GRID grid.1003.2, Queensland Brain Institute, , The University of Queensland, ; Brisbane, QLD 4072 Australia
[101
]ISNI 0000 0004 0386 9924, GRID grid.32224.35, Center for Human Genetic Research, Massachusetts General Hospital, ; Boston, MA USA
[102
]ISNI 0000 0004 0386 9924, GRID grid.32224.35, Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General
Hospital, ; Boston, MA USA
[103
]ISNI 0000 0004 1936 8948, GRID grid.4991.5, Medical Research Council Population Health Research Unit at the University of Oxford,
; Oxford, UK
[104
]ISNI 0000 0004 1936 8948, GRID grid.4991.5, Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department
of Population Health, Big Data Institute, , University of Oxford, ; Oxford, UK
[105
]ISNI 0000 0001 0440 1440, GRID grid.410556.3, National Institute for Health Research Oxford Biomedical Research Centre, , Oxford University Hospital, ; Oxford, UK
[106
]ISNI 0000000121901201, GRID grid.83440.3b, Division of Psychiatry, , University College of London, ; London, W1T 7NF UK
[107
]ISNI 0000000121901201, GRID grid.83440.3b, UCL Genetics Institute, University College London, ; London, WC1E 6BT UK
[108
]ISNI 0000 0004 0623 9987, GRID grid.411843.b, Department of Cardiology, Clinical Sciences, , Lund University and Skåne University Hospital, ; Lund, Sweden
[109
]ISNI 0000 0001 0930 2361, GRID grid.4514.4, Wallenberg Center for Molecular Medicine and Lund University Diabetes Center, , Lund University, ; Lund, Sweden
[110
]ISNI 0000 0004 1936 7558, GRID grid.189504.1, Sections of Cardiology, Preventive Medicine and Epidemiology, Department of Medicine,
, Boston University Schools of Medicine and Public Health, ; Boston, MA USA
[111
]ISNI 0000 0000 9244 0345, GRID grid.416353.6, Bart’s Heart Centre, St. Bartholomew’s Hospital, ; London, UK